Biotin Rat Anti-Mouse CD38 Antibody (90)
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1,2'-phospho-ADP-ribosyl cyclase,2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase,2'-phospho-cyclic-ADP-ribose transferase,ADP-ribosyl cyclase 1 (ADPRC 1),Cyclic ADP-ribose hydrolase 1 (cADPR hydrolase 1),Cd38
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宿主来源
Rat抗原名称
CD38分子别名
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1; 2'-phospho-ADP-ribosyl cyclase; 2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase; 2'-phospho-cyclic-ADP-ribose transferase; ADP-ribosyl cyclase 1 (ADPRC 1); Cyclic ADP-ribose hydrolase 1 (cADPR hydrolase 1); Cd38细胞定位
MembraneAccession
P56528克隆号
90抗体类型
Rat mAb抗体同种型
IgG2a,k反应种属 ?
Ms阳性样本
C57BL/6 mouse splenocytes纯化方式
Protein G浓度
0.2 mg/ml标记
Biotin性状
Liquid缓冲体系
PBS pH7.4, 0.03% Proclin 300
储存条件
12 months from date of receipt / reconstitution, 2 to 8 °C as supplied
应用
FCM
稀释度
应用 稀释度 推荐种属 FCM 5μl per million cells in 100μl volume Ms
CD38 is a multifunctional type II transmembrane glycoprotein expressed on immune cells and in various tissues, acting both as a receptor and an enzyme that converts NAD⁺ into cyclic ADP-ribose and ADP-ribose to regulate intracellular calcium signaling, immune cell activation, proliferation, and migration, and is also a key therapeutic target in multiple myeloma due to its high expression on malignant plasma cells and its role in modulating NAD⁺ levels linked to aging and metabolic processes.
流式分析
Flow cytometric analysis of Mouse CD38 expression on C57BL/6 mouse splenocytes. C57BL/6 mouse splenocytes were stained with Alexa Fluor® 647 Rat Anti-Mouse CD3 Antibody and either Biotin Mouse IgG2a, κ Isotype Control (Left panel) or SDT Biotin Rat Anti-Mouse CD38 Antibody (Right panel) at 5μl/test followed by Sav-PE. Flow cytometry and data analysis were performed using BD FACSymphony™ A1 and FlowJo™ software.
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