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Alexa Fluor® 700 Mouse Anti-Human CD62P Antibody (S-921-3)

P-selectin,CD62 antigen-like family member P,Granule membrane protein 140 (GMP-140),Leukocyte-endothelial cell adhesion molecule 3 (LECAM3),Platelet activation dependent granule-external membrane protein (PADGEM),GMRP,GRMP,SELP

价格 ￥880.00 （ 1-2周）
货号 S0B8407
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产品介绍

产品介绍 评论(0)

产品规格

  • 宿主来源

    Mouse

  • 抗原名称

    CD62P

  • 分子别名

    P-selectin; CD62 antigen-like family member P; Granule membrane protein 140 (GMP-140); Leukocyte-endothelial cell adhesion molecule 3 (LECAM3); Platelet activation dependent granule-external membrane protein (PADGEM); GMRP; GRMP; SELP

  • 免疫原

    Recombinant Protein

  • 细胞定位

    Cell membrane

  • Accession

    P16109

  • 克隆号

    S-921-3

  • 抗体类型

    Mouse mAb

  • 抗体同种型

    IgG1,k

  • 反应种属 ?

    Hu

  • 阳性样本

    human peripheral blood

  • 纯化方式

    Protein G

  • 浓度

    0.2 mg/ml

  • 标记

    Alexa Fluor® 700

  • 性状

    Liquid

  • 缓冲体系

    PBS, 1% BSA, 0.3% Proclin 300

  • 储存条件

    12 months from date of receipt / reconstitution, 2 to 8 °C as supplied

  • 应用

    FCM

  • 稀释度

    应用 稀释度 推荐种属
    FCM 5μl per million cells in 100μl volume Hu
背景介绍

  • CD62P, also known as P-selectin, is a 140 kDa type I transmembrane glycoprotein that plays a crucial role in cell adhesion and immune responses. It is stored in α-granules of platelets and Weibel-Palade bodies of endothelial cells, and is rapidly relocated to the cell surface upon activation by stimuli such as thrombin or histamine. CD62P mediates the initial adhesion and rolling of leukocytes on endothelial cells during inflammation and facilitates interactions between activated platelets and neutrophils or monocytes. It binds to specific carbohydrate ligands on leukocytes in a calcium-dependent manner. Additionally, CD62P is used as a marker for platelet activation and has potential diagnostic value in various diseases.

  • 流式分析

    • Flow cytometric analysis of Human CD62P expression on human peripheral blood. Human peripheral blood were stained with FITC Mouse Anti-Human CD41a Antibody and either Alexa Fluor® 700 Mouse IgG1, κ Isotype Control (Left panel) or SDT Alexa Fluor® 700 Mouse Anti-Human CD62P (Right panel) at 5μl/test. Flow cytometry and data analysis were performed using Agilent NovoCyte Quanteon and FlowJo™ software.

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