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Mouse抗原名称
CD31分子别名
Platelet endothelial cell adhesion molecule; PECAM-1; EndoCAM; GPIIA'; PECA1; PECAM1免疫原
Recombinant Protein细胞定位
Cell membraneAccession
P16284克隆号
S-934-6抗体类型
Mouse mAb抗体同种型
IgG1,k反应种属 ?
Hu阳性样本
Human PBMC纯化方式
Protein G浓度
0.2 mg/ml标记
Alexa Fluor® 488性状
Liquid缓冲体系
PBS, 1% BSA, 0.3% Proclin 300
储存条件
12 months from date of receipt / reconstitution, 2 to 8 °C as supplied
应用
FCM
稀释度
应用 稀释度 推荐种属 FCM 5μl per million cells in 100μl volume Hu
CD31, also known as platelet endothelial cell adhesion molecule-1 (PECAM-1), is a 130 kDa transmembrane glycoprotein of the immunoglobulin superfamily composed of six extracellular Ig-like domains, a single transmembrane region, and a cytoplasmic tail with multiple phosphorylation sites, and it is constitutively expressed on endothelial cells, platelets, leukocytes, and hematopoietic stem cells, where it mediates homophilic and heterophilic cell–cell adhesion, facilitates leukocyte transendothelial migration, regulates vascular permeability, and plays an essential role in developmental and pathological angiogenesis by promoting endothelial tube formation and neovessel stabilization.
流式分析
Flow cytometric analysis of Human CD31 expression on Human PBMC (human peripheral blood mononuclear cells). Human PBMC was stained with Alexa Fluor® 488 Mouse IgG1, κ Isotype Control (Left Panel) and SDT Alexa Fluor® 488 Mouse Anti-Human CD31 antibody (Right Panel) at 5 μl/test. Flow cytometry and data analysis were performed using BD FACSymphony™ A1 and FlowJo™ software.
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