Rat Anti-Mouse TIM-4 Antibody (S-R685)
T-cell immunoglobulin and mucin domain-containing protein 4,TIMD-4,Spleen,mucin-containing,knockout of lymphotoxin protein (SMUCKLER),T-cell immunoglobulin mucin receptor 4 (TIM-4),T-cell membrane protein 4,Tim4,Timd4
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宿主来源
Rat抗原名称
TIM-4分子别名
T-cell immunoglobulin and mucin domain-containing protein 4; TIMD-4; Spleen; mucin-containing; knockout of lymphotoxin protein (SMUCKLER); T-cell immunoglobulin mucin receptor 4 (TIM-4); T-cell membrane protein 4; Tim4; Timd4细胞定位
MembraneAccession
Q6U7R4克隆号
S-R685抗体类型
Rat mAb抗体同种型
IgG2a,k反应种属 ?
Ms阳性样本
Fresh BALB/c mouse peritoneal exudates纯化方式
Protein G浓度
2 mg/ml标记
Unconjugated性状
Liquid缓冲体系
PBS pH7.4
储存条件
12 months from date of receipt / reconstitution, 2 to 8 °C as supplied
应用
FCM
稀释度
应用 稀释度 推荐种属 FCM 1:200 Ms
TIM-4 (T-cell immunoglobulin and mucin domain 4) is a phosphatidylserine-recognizing receptor expressed mainly on antigen-presenting cells such as macrophages and dendritic cells, where it mediates the efficient clearance of apoptotic cells, thereby maintaining immune homeostasis, and can also bind to TIM-1 on activated T cells to either co-stimulate or inhibit T-cell proliferation and cytokine production in a context- and dose-dependent manner, thus regulating both innate and adaptive immunity and influencing diseases ranging from infection and allergy to cancer and ischemia–reperfusion injury.
流式分析
Flow cytometric analysis of Fresh BALB/c mouse peritoneal exudates cells labelling Mouse TIM-4 antibody at 1/200 dilution (1 μg) / (Right panel) compared with a Rat IgG2a, κ Isotype Control / (Left panel). Goat Anti-Rat IgG Alexa Fluor® 647 was used as the secondary antibody. Then cells were stained with CD11b - Brilliant Violet 421™ Antibody separately.
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