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Rat Anti-Mouse CD309 Antibody (S-R706)

Vascular endothelial growth factor receptor 2,VEGFR-2,Fetal liver kinase 1 (FLK-1),Kinase NYK,Protein-tyrosine kinase receptor flk-1,Flk-1,Flk1,Kdr

价格 220.00 1-2周
货号 S0B8356
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产品规格
  • 宿主来源

    Rat
  • 抗原名称

    CD309
  • 分子别名

    Vascular endothelial growth factor receptor 2; VEGFR-2; Fetal liver kinase 1 (FLK-1); Kinase NYK; Protein-tyrosine kinase receptor flk-1; Flk-1; Flk1; Kdr
  • 细胞定位

    Cell junction
  • Accession

    P35918
  • 克隆号

    S-R706
  • 抗体类型

    Rat mAb
  • 抗体同种型

    IgG2a,k
  • 反应种属 ?

    Ms
  • 阳性样本

    bEnd.3
  • 纯化方式

    Protein G
  • 浓度

    2 mg/ml
  • 标记

    Unconjugated
  • 性状

    Liquid
  • 缓冲体系

    PBS pH7.4

  • 储存条件

    12 months from date of receipt / reconstitution, 2 to 8 °C as supplied

  • 应用

    FCM

  • 稀释度

    应用 稀释度 推荐种属
    FCM 1:200 Ms
背景介绍
  • CD309, also known as VEGFR-2 or KDR, is a type III receptor tyrosine kinase that functions as the primary mediator of VEGF-induced angiogenesis, endothelial cell proliferation, migration, survival, and vascular permeability by activating downstream signaling pathways including MAPK, PI3K-Akt, and PLCγ1 upon ligand binding.

  • 流式分析

    • Flow cytometric analysis of bEnd.3 (Mouse brain endothelioma, Right) / NIH/3T3 (Mouse embryonic fibroblast, Left) cells labelling CD309 antibody at 1/200 dilution (1 μg)/ (Red) compared with a Rat monoclonal IgG (Black) isotype control and an unlabelled control (cells without incubation with primary antibody and secondary antibody) (Blue). Goat Anti - Rat IgG PE was used as the secondary antibody.
      Negative control: NIH/3T3

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