分享产品介绍 评论(0)
分子别名
Membrane cofactor protein; TLX; Trophoblast leukocyte common antigen; MCP; MIC10细胞定位
Cell membraneAccession
P15529克隆号
S-3061抗体类型
Mouse mAb抗体同种型
IgG2a,k反应种属 ?
Hu纯化方式
Protein A浓度
2 mg/ml标记
Unconjugated性状
Liquid缓冲体系
PBS pH7.4
储存条件
12 months from date of receipt / reconstitution, 2 to 8 °C as supplied
应用
FCM
稀释度
应用 稀释度 推荐种属 FCM 1:200 Hu
CD46, also known as membrane cofactor protein (MCP), is a type I transmembrane glycoprotein expressed on almost all human nucleated cells that protects host tissues from complement-mediated injury by acting as a cofactor for factor I–mediated proteolytic inactivation of the complement fragments C3b and C4b, and also modulates adaptive immunity by driving IFN-γ–biased Th1 responses and subsequent IL-10–producing T-regulatory cell differentiation, while serving as a cellular receptor for multiple pathogens including measles virus, adenoviruses, HHV-6, and pathogenic Neisseria.
流式分析
Flow cytometric analysis of Human PBMC (human peripheral blood mononuclear cells) labelling Human CD46 antibody at 1/200 dilution (1 μg) / (Red) compared with a Mouse IgG2a, κ (Black) Isotype Control. Goat Anti - Mouse IgG Alexa Fluor® 488 was used as the secondary antibody.
评论(0)