Biotin Mouse Anti-Human CD197 Antibody (S-R704)
C-C chemokine receptor type 7,C-C CKR-7,CC-CKR-7,CCR-7,BLR2,CDw197,Epstein-Barr virus-induced G-protein coupled receptor 1 (EBI1,EBV-induced G-protein coupled receptor 1),MIP-3 beta receptor,CMKBR7,EBI1,EVI1,CCR7
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分子别名
C-C chemokine receptor type 7; C-C CKR-7; CC-CKR-7; CCR-7; BLR2; CDw197; Epstein-Barr virus-induced G-protein coupled receptor 1 (EBI1; EBV-induced G-protein coupled receptor 1); MIP-3 beta receptor; CMKBR7; EBI1; EVI1; CCR7细胞定位
Cell membraneAccession
P32248克隆号
S-R704抗体类型
Mouse mAb抗体同种型
IgG2a,k反应种属 ?
Hu纯化方式
Protein A浓度
0.2 mg/ml标记
Biotin性状
Liquid缓冲体系
PBS pH7.4, 0.03% Proclin 300
储存条件
12 months from date of receipt / reconstitution, 2 to 8 °C as supplied
应用
FCM
稀释度
应用 稀释度 推荐种属 FCM 5μl per million cells in 100μl volume Hu
CD197, also known as CCR7 (C-C motif chemokine receptor 7) or BLR2, is a G protein-coupled receptor that plays a crucial role in immune cell migration and function. It is expressed on activated T cells, B cells, and dendritic cells, and is significantly upregulated in B cells following Epstein-Barr virus infection. CD197 binds chemokines such as CCL19 and CCL21, mediating the migration of memory T cells to lymph nodes and the maturation of dendritic cells. It also serves as a biomarker for certain immune responses and is involved in the regulation of T cell homeostasis and chronic inflammation.
流式分析
Flow cytometric analysis of Human CD197 expression on Human PBMC (human peripheral blood mononuclear cells). Human PBMC were stained with Brilliant Violet 421™ Mouse Anti-Human CD3 Antibody and either Biotin Mouse IgG2a, κ Isotype Control (Left panel) or SDT Biotin Mouse Anti-Human CD197 Antibody (Right panel) at 5 μl/test followed by Sav-iFluor 488. Flow cytometry and data analysis were performed using BD FACSymphony™ A1 and FlowJo™ software.
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