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宿主来源
Mouse抗原名称
IgM分子别名
Immunoglobulin heavy constant mu; Ig mu chain C region; Ig mu chain C region BOT; Ig mu chain C region GAL; Ig mu chain C region OU; IGHM细胞定位
Cell membrane, SecretedAccession
P01871克隆号
S-3031抗体类型
Mouse mAb抗体同种型
IgG1,k同型对照
S0B80038反应种属 ?
Hu阳性样本
Human PBMC纯化方式
Protein G浓度
0.1 mg/ml标记
APC性状
Liquid缓冲体系
PBS, 1% BSA, 0.3% Proclin 300
储存条件
12 months from date of receipt / reconstitution, 2 to 8 °C as supplied
应用
FCM
稀释度
应用 稀释度 推荐种属 FCM 1μl per million cells in 100μl volume Hu
Human IgM is the first type of antibody produced by the body in response to an initial exposure to an antigen. It is a large, pentameric molecule, composed of five identical Y-shaped units linked together. Each IgM molecule has ten antigen-binding sites, which allows it to be highly effective at agglutinating pathogens. IgM is primarily found in the bloodstream and plays a crucial role in the early stages of the immune response. It can activate the complement system, enhancing the ability to eliminate pathogens. Additionally, the presence of IgM antibodies in diagnostic tests often indicates a recent infection, as it appears earlier than other types of antibodies like IgG.
免疫印迹
流式分析
Flow cytometric analysis of IgM expression on Human PBMC. Human PBMC were stained with Brilliant Violet 421™ Mouse Anti-Human CD19 Antibody and either APC Mouse IgG1, κ Isotype Control (Left panel) or SDT APC Mouse Anti-Human IgM Antibody (Right panel) at 1 μl/test. Total viable cells, as determined by Fixable Viability Dye 515 (S0D0013), were used for analysis. Flow cytometry and data analysis were performed using BD FACSymphony™ A1 and FlowJo™ software.
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