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产品中心 流式试剂&相关 流式抗体

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Biotin Rat Anti-Mouse CD309 Antibody (S-R706)

Vascular endothelial growth factor receptor 2,VEGFR-2,Fetal liver kinase 1 (FLK-1),Kinase NYK,Protein-tyrosine kinase receptor flk-1,Flk-1,Flk1,Kdr

价格 ￥300.00 （ 1-2周）
货号 S0B80683
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产品介绍

产品介绍 评论(0)

产品规格

  • 宿主来源

    Rat

  • 抗原名称

    CD309

  • 分子别名

    Vascular endothelial growth factor receptor 2; VEGFR-2; Fetal liver kinase 1 (FLK-1); Kinase NYK; Protein-tyrosine kinase receptor flk-1; Flk-1; Flk1; Kdr

  • 细胞定位

    Cell junction

  • Accession

    P35918

  • 克隆号

    S-R706

  • 抗体类型

    Rat mAb

  • 抗体同种型

    IgG2a,k

  • 反应种属 ?

    Ms

  • 阳性样本

    bEnd.3

  • 纯化方式

    Protein G

  • 浓度

    0.5 mg/ml

  • 标记

    Biotin

  • 性状

    Liquid

  • 缓冲体系

    PBS pH7.4, 0.09% sodium azide

  • 储存条件

    12 months from date of receipt / reconstitution, 2 to 8 °C as supplied

  • 应用

    FCM

  • 稀释度

    应用 稀释度 推荐种属
    FCM 1μg per million cells in 100μl volume Ms
背景介绍

  • CD309, also known as VEGFR-2 or KDR, is a type III receptor tyrosine kinase that functions as the primary mediator of VEGF-induced angiogenesis, endothelial cell proliferation, migration, survival, and vascular permeability by activating downstream signaling pathways including MAPK, PI3K-Akt, and PLCγ1 upon ligand binding.

  • 流式分析

    • Flow cytometric analysis of CD309 expression on bEnd.3 (Mouse brain endothelioma, right) / NIH/3T3 (Mouse embryonic fibroblast, left). Cells from bEnd.3 / NIH/3T3 were stained with either Biotin Rat IgG2a, k Isotype Control (black line histogram) or SDT Biotin Rat Anti-Mouse CD309 Antibody (red line histogram) at 2 μl/test followed by Sav-APC. Flow cytometry and data analysis were performed using BD FACSymphony™ A1 and FlowJo™ software.

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