Biotin Armenian hamster Anti-Mouse VISTA (PD-1H) Antibody (S-R596)
V-type immunoglobulin domain-containing suppressor of T-cell activation,Platelet receptor Gi24,V-set domain-containing immunoregulatory receptorImported,V-set immunoregulatory receptorImported,Dies1,PD-1H,Vsir
分享产品介绍 评论(0)
宿主来源
Armenian hamster抗原名称
VISTA分子别名
V-type immunoglobulin domain-containing suppressor of T-cell activation; Platelet receptor Gi24; V-set domain-containing immunoregulatory receptorImported; V-set immunoregulatory receptorImported; Dies1; PD-1H; Vsir细胞定位
Cell membraneAccession
Q9D659克隆号
S-R596抗体类型
Recombinant mAb抗体同种型
IgG同型对照
S0B80066反应种属 ?
Ms阳性样本
C57BL/6 mouse splenocytes纯化方式
Protein G浓度
0.5 mg/ml标记
Biotin性状
Liquid缓冲体系
PBS pH7.4, 0.09% sodium azide
储存条件
12 months from date of receipt / reconstitution, 2 to 8 °C as supplied
应用
FCM
稀释度
应用 稀释度 推荐种属 FCM 1μg per million cells in 100μl volume Ms
VISTA (V-domain Ig suppressor of T-cell activation), also known as B7-H5, PD-1H, C10orf54, Dies1, Gi24 or SISP1, is a type I transmembrane immune-checkpoint protein of the B7-CD28 family that is highly expressed on myeloid and granulocytic cells and at lower levels on CD4+ and CD8+ T cells; it functions both as an inhibitory receptor and as a ligand on antigen-presenting cells to suppress T-cell activation, maintain peripheral tolerance, modulate innate and adaptive anti-tumour immunity, and may additionally regulate embryonic stem-cell differentiation via BMP4 inhibition and stimulate MMP14-mediated MMP2 activation.
流式分析
Flow cytometric analysis of mouse VISTA(PD-1H) expression on C57BL/6 mouse splenocytes. C57BL/6 mouse splenocytes were stained with APC Rat Anti-Mouse CD8 Antibody and either Biotin Armenian hamster IgG Isotype Control (left panel) or SDT Biotin Armenian hamster Anti-Mouse VISTA (PD-1H) Antibody (right panel) at 2 μl/test followed by Sav-iFluor 488. Flow cytometry and data analysis were performed using Agilent NovoCyte Quanteon and FlowJo™ software.
评论(0)