Armenian hamster Anti-Mouse VISTA (PD-1H) Antibody (S-R596)
V-type immunoglobulin domain-containing suppressor of T-cell activation,Platelet receptor Gi24,V-set domain-containing immunoregulatory receptorImported,V-set immunoregulatory receptorImported,Dies1,PD-1H,Vsir
分享产品介绍 评论(0)
宿主来源
Armenian hamster抗原名称
VISTA分子别名
V-type immunoglobulin domain-containing suppressor of T-cell activation; Platelet receptor Gi24; V-set domain-containing immunoregulatory receptorImported; V-set immunoregulatory receptorImported; Dies1; PD-1H; Vsir细胞定位
Cell membraneAccession
Q9D659克隆号
S-R596抗体类型
Recombinant mAb抗体同种型
IgG反应种属 ?
Ms阳性样本
C57BL/6 mouse splenocytes纯化方式
Protein G浓度
2 mg/ml标记
Unconjugated性状
Liquid缓冲体系
PBS pH7.4
储存条件
12 months from date of receipt / reconstitution, 2 to 8 °C as supplied
应用
FCM
稀释度
应用 稀释度 推荐种属 FCM 1:200 Ms
VISTA (V-domain Ig suppressor of T-cell activation), also known as B7-H5, PD-1H, C10orf54, Dies1, Gi24 or SISP1, is a type I transmembrane immune-checkpoint protein of the B7-CD28 family that is highly expressed on myeloid and granulocytic cells and at lower levels on CD4+ and CD8+ T cells; it functions both as an inhibitory receptor and as a ligand on antigen-presenting cells to suppress T-cell activation, maintain peripheral tolerance, modulate innate and adaptive anti-tumour immunity, and may additionally regulate embryonic stem-cell differentiation via BMP4 inhibition and stimulate MMP14-mediated MMP2 activation.
流式分析
Flow cytometric analysis of C57BL/6 mouse splenocytes labeled with Mouse VISTA antibody at 1/200 dilution (1 μg) / (right panel) compared with an Armenian hamster IgG Isotype Control / (left panel). Goat Anti- Armenian hamster IgG Alexa Fluor® 488 was used as the secondary antibody. Then cells were stained with CD8 – APC antibody separately. Flow cytometry and data analysis were performed using Agilent NovoCyte Quanteon and FlowJo™ software.
评论(0)