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Alexa Fluor® 647 Mouse Anti-Human CD138 Antibody (S-3450)

Syndecan-1,SYND1,SDC,SDC1

价格 500.00 1-2周
货号 S0B80644
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产品介绍 评论(0)

产品规格
  • 宿主来源

    Mouse
  • 抗原名称

    CD138
  • 分子别名

    Syndecan-1; SYND1; SDC; SDC1
  • 细胞定位

    Membrane
  • Accession

    P18827
  • 克隆号

    S-3450
  • 抗体类型

    Mouse mAb
  • 抗体同种型

    IgG1,k
  • 同型对照

    S0B5964
  • 反应种属 ?

    Hu
  • 阳性样本

    U266B1
  • 纯化方式

    Protein G
  • 浓度

    0.2 mg/ml
  • 标记

    Alexa Fluor® 647
  • 性状

    Liquid
  • 缓冲体系

    PBS, 1% BSA, 0.09% sodium azide

  • 储存条件

    12 months from date of receipt / reconstitution, 2 to 8 °C as supplied

  • 应用

    FCM

  • 稀释度

    应用 稀释度 推荐种属
    FCM 5μl per million cells in 100μl volume Hu
背景介绍
  • CD138, also known as syndecan-1, is a transmembrane heparan sulfate proteoglycan that plays a crucial role in cell adhesion, migration, and signaling. It is predominantly expressed on the surface of plasma cells and certain epithelial cells. In plasma cells, CD138 serves as a valuable marker for their identification and isolation, aiding in the diagnosis and study of plasma cell disorders such as multiple myomael. On epithelial cells, it contributes to the maintenance of cell structure and function by interacting with extracellular matrix components and growth factors. Additionally, CD138 is involved in various biological processes including wound healing, inflammation, and cancer progression. Its ability to bind and modulate the activity of numerous proteins makes it an important factor in cellular communication and regulation.

  • 流式分析

    • Flow cytometric analysis of Human CD138 expression on U266B1 cells. Cells from the U266B1 (Human multiple myeloma B lymphocyte, right) or Jurkat (Human T cell leukemia T lymphocyte, left) were stained with either Alexa Fluor® 647 Mouse IgG1, k Isotype Control (black line histogram) or SDT Alexa Fluor® 647 Mouse Anti-Human CD138 Antibody (red line histogram) at 5 μl/test. Flow cytometry and data analysis were performed using BD FACSymphony™ A1 and FlowJo™ software.

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