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宿主来源
Rat抗原名称
CD107b分子别名
Lysosome-associated membrane glycoprotein 2; LAMP-2; Lysosome-associated membrane protein 2; CD107 antigen-like family member B; Lysosomal membrane glycoprotein type B (LGP-B); Lamp2细胞定位
Lysosome, Endosome, Cell membraneAccession
P17047克隆号
M3/84抗体类型
Rat mAb抗体同种型
IgG1,k反应种属 ?
Ms阳性样本
C57BL/6 mouse BMDM纯化方式
Protein G浓度
0.5 mg/ml标记
Biotin性状
Liquid缓冲体系
PBS pH7.4, 0.09% sodium azide
储存条件
12 months from date of receipt / reconstitution, 2 to 8 °C as supplied
应用
FCM
稀释度
应用 稀释度 推荐种属 FCM 1μg per million cells in 100μl volume Ms
CD107b, also known as lysosome-associated membrane protein 2 (LAMP-2), is a highly glycosylated type I transmembrane protein with a molecular weight of approximately 105–120 kDa. It is primarily located in the lysosomal/endosomal membranes of nearly all cells and can be transiently expressed on the surface of activated platelets, activated lymphocytes, and some tumor cell lines. LAMP-2 plays crucial roles in various cellular processes, including cell adhesion, cellular homeostasis, autophagocytosis, antigen presentation, and protection of the lysosome. Additionally, it may be involved in tumor cell metastasis by mediating adhesion to vascular endothelium.
流式分析
Flow cytometric analysis of CD107b expression on C57BL/6 mouse BMDMs. C57BL/6 mouse BMDMs were stained with PE Rat Anti-Mouse F4/80 Antibody and either Biotin Rat IgG1, κ Isotype Control (left panel) or SDT Biotin Rat Anti-Mouse CD107b Antibody (right panel) at 2 μl/test followed by Sav-iFluor 488. Flow cytometry and data analysis were performed using BD FACSymphony™ A1 and FlowJo™ software.
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