分享产品介绍 评论(0)
宿主来源
Armenian hamster抗原名称
CD49B分子别名
Integrin alpha-2; CD49 antigen-like family member B; Collagen receptor; Platelet membrane glycoprotein Ia (GPIa); VLA-2 subunit alpha; Itga2细胞定位
Membrane克隆号
S-R688抗体类型
Recombinant mAb抗体同种型
IgG反应种属 ?
Rt阳性样本
SD Rat splenocytes纯化方式
Protein G浓度
2 mg/ml标记
Unconjugated性状
Liquid缓冲体系
PBS pH7.4
储存条件
12 months from date of receipt / reconstitution, 2 to 8 °C as supplied
应用
FCM
稀释度
应用 稀释度 推荐种属 FCM 1:200 Rt
CD49b, also known as integrin alpha-2, is a protein encoded by the CD49b gene in humans. It is a subunit of the integrin receptor family, specifically forming the VLA-2 receptor when paired with the beta-1 subunit. This receptor is primarily involved in mediating cell adhesion to collagen and laminin, playing a crucial role in various biological processes such as platelet aggregation, cell migration, and tissue repair. CD49b is expressed on various cell types, including natural killer cells and a subset of T cells, and has been implicated in immune responses and cancer progression. In cancer research, CD49b has been identified as a potential therapeutic target due to its role in promoting cell proliferation and invasion in certain malignancies.
流式分析
Flow cytometric analysis of SD Rat splenocytes labelling Rat CD49B antibody at 1/2000 (0.1 μg) dilution (Right) compared with a Armenian hamster monoclonal IgG isotype control (Left). Followed by Anti-Armenian Hamster IgG (H+L) biotin and Sav-PE. Then cells were stained with NK-1.1 - APC separately. Total viable cells, as determined by Fixable Viability Dye 452 (S0D0021), were used for analysis.
评论(0)