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宿主来源
Mouse抗原名称
CD166分子别名
CD166 antigen; Activated leukocyte cell adhesion molecule; CD166; MEMD; ALCAM细胞定位
Cell membraneAccession
Q13740克隆号
S-2869抗体类型
Mouse mAb抗体同种型
IgG1,k反应种属 ?
Hu阳性样本
Human PBMC纯化方式
Protein G浓度
0.2 mg/ml标记
Alexa Fluor® 700性状
Liquid缓冲体系
PBS, 1% BSA, 0.09% sodium azide
储存条件
12 months from date of receipt / reconstitution, 2 to 8 °C as supplied
应用
FCM
稀释度
应用 稀释度 推荐种属 FCM 5μl per million cells in 100μl volume Hu
CD166, also known as Activated Leukocyte Cell Adhesion Molecule (ALCAM), is a type I transmembrane glycoprotein belonging to the immunoglobulin superfamily. It is encoded by the ALCAM gene and is involved in both homotypic and heterotypic cell adhesion. CD166 is expressed on various cell types, including activated T cells, epithelial cells, fibroblasts, and neurons. It plays a crucial role in mediating adhesion interactions between thymic epithelial cells and CD6+ cells during T cell development. Additionally, CD166 is overexpressed in several types of tumors and serves as a potential cancer stem cell marker, making it a target for cancer research and therapy.
流式分析
Flow cytometric analysis of human CD166 expression on human PBMCs (human peripheral blood mononuclear cells). Human PBMCs were stained with Brilliant Violet 421™ Mouse Anti-Human CD14 Antibody and SDT Alexa Fluor® 700 Mouse Anti-Human CD166 Antibody at 5 μl/test. Flow cytometry and data analysis were performed using Agilent NovoCyte Quanteon and FlowJo™ software.
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