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宿主来源
Rat抗原名称
CD8β分子别名
T-cell surface glycoprotein CD8 beta chain; Lymphocyte antigen 3; T-cell membrane glycoprotein Ly-3; T-cell surface glycoprotein Lyt-3; Cd8b1; Ly-3; Lyt-3; Lyt3; Cd8b细胞定位
MembraneAccession
P10300克隆号
53-5.8抗体类型
Mouse mAb抗体同种型
IgG1,k同型对照
S0B5964反应种属 ?
Ms阳性样本
C57BL/6 mouse splenocytes纯化方式
Protein G浓度
0.5 mg/ml标记
Alexa Fluor® 647性状
Liquid缓冲体系
PBS, 1% BSA, 0.09% sodium azide
储存条件
12 months from date of receipt / reconstitution, 2 to 8 °C as supplied
应用
FCM
稀释度
应用 稀释度 推荐种属 FCM 1μg per million cells in 100μl volume Ms
CD8β is a protein that, along with CD8α, forms the CD8 co - receptor complex on the surface of cytotoxic T cells. This complex plays a crucial role in the immune response by facilitating the interaction between cytotoxic T cells and antigen - presenting cells. CD8β helps stabilize the binding of the T cell receptor to MHC class I molecules on the antigen - presenting cell, thereby enhancing the specificity and efficiency of the T cell - mediated immune response. This interaction is essential for the activation of cytotoxic T cells, which can then target and destroy infected or malignant cells.
流式分析
Flow cytometric analysis of Mouse CD8β expression on C57BL/6 mouse splenocytes. C57BL/6 mouse splenocytes were stained with Brilliant Violet 711™ Rat Anti-Mouse CD8a Antibody and either Alexa Fluor® 647 Rat IgG1, k Isotype Control (left panel) or SDT Alexa Fluor® 647 Rat Anti-Mouse CD8β Antibody (right panel) at 2 μl/test. Flow cytometry and data analysis were performed using Agilent NovoCyte Quanteon and FlowJo™ software.
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