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宿主来源
Rabbit抗原名称
CD86分子别名
T-lymphocyte activation antigen CD86; Activation B7-2 antigen; B70; BU63; CTLA-4 counter-receptor B7.2; FUN-1; CD28LG2细胞定位
Cell membraneAccession
P42081克隆号
S-990-1抗体类型
Recombinant mAb抗体同种型
IgG同型对照
S0B1550反应种属 ?
Hu阳性样本
uman Peripheral Blood cells纯化方式
Protein A浓度
0.2 mg/ml标记
Pacific Blue性状
Liquid缓冲体系
PBS, 1% BSA, 0.09% sodium azide
储存条件
12 months from date of receipt / reconstitution, 2 to 8 °C as supplied
应用
FCM
稀释度
应用 稀释度 推荐种属 FCM 5μl per million cells in 100μl volume Hu
CD86, also known as B7-2, is a co-stimulatory molecule expressed on the surface of antigen-presenting cells (APCs) such as dendritic cells, macrophages, and B cells. It plays a crucial role in the immune response by interacting with CD28 on T cells to provide a necessary co-stimulatory signal for T cell activation, proliferation, and differentiation. Additionally, CD86 can also bind to CTLA-4, an inhibitory receptor on T cells, thereby regulating immune responses and maintaining immune homeostasis. This dual functionality makes CD86 a key target in immunotherapy research, particularly in the development of cancer treatments and autoimmune disease management strategies.
流式分析
Flow cytometric analysis of Human CD86 expression on Human Peripheral Blood cells. Human Peripheral Blood cells were stained with APC Mouse Anti-Human CD14 Antibody and either Pacific Blue Rabbit IgG Isotype Control (left panel) or SDT Pacific Blue Rabbit Anti-Human CD86 Antibody (right panel) at 5 μl/test. Flow cytometry and data analysis were performed using BD FACSymphony™ A1 and FlowJo™ software.
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