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Alexa Fluor® 488 Rat Anti-Mouse CD2 Antibody (RM2-5)

T-cell surface antigen CD2,LFA-2,LFA-3 receptor,Lymphocyte antigen 37 (Ly-37),T-cell surface antigen T11/Leu-5,Ly-37,Cd2

价格 300.00 供应商现货 : 3-5个工作日
货号 S0B80346
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产品规格
  • 宿主来源

    Rat
  • 抗原名称

    CD2
  • 分子别名

    T-cell surface antigen CD2; LFA-2; LFA-3 receptor; Lymphocyte antigen 37 (Ly-37); T-cell surface antigen T11/Leu-5; Ly-37; Cd2
  • 细胞定位

    Cell membrane
  • Accession

    P08920
  • 克隆号

    RM2-5
  • 抗体类型

    Rat mAb
  • 抗体同种型

    IgG2b,k
  • 同型对照

    S0B5536
  • 反应种属 ?

    Ms
  • 阳性样本

    C57BL/6 mouse splenocytes
  • 纯化方式

    Protein G
  • 浓度

    0.5 mg/ml
  • 标记

    Alexa Fluor® 488
  • 性状

    Liquid
  • 缓冲体系

    PBS, 1% BSA, 0.3% Proclin 300

  • 储存条件

    12 months from date of receipt / reconstitution, 2 to 8 °C as supplied

  • 应用

    FCM

  • 稀释度

    应用 稀释度 推荐种属
    FCM 1μg per million cells in 100μl volume Ms
背景介绍
  • CD2, also known as the T-cell rosette receptor or LFA-2, is a type I membrane protein predominantly expressed on thymocytes and mature T cells. It functions as an adhesion molecule that binds to CD58 (LFA-3) on antigen-presenting cells (APCs), facilitating T-cell receptor (TCR) binding and signal transduction, which is crucial for T-cell activation and immune responses.

  • 流式分析

    • Flow cytometric analysis of CD2 expression on C57BL/6 mouse splenocytes. C57BL/6 mouse splenocytes were stained with Brilliant Violet 421™ Rat Anti-Mouse CD19 and either Alexa Fluor® 488 Mouse IgG2b, κ Isotype Control (left panel) or SDT Alexa Fluor® 488 Rat Anti-Mouse CD2 Antibody (right panel) at 2 μl/test. Flow cytometry and data analysis were performed using Agilent NovoCyte Quanteon and FlowJo™ software.

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