Biotin Mouse Anti-Human CD122 Antibody (S-2880)
Interleukin-2 receptor subunit beta,IL-2 receptor subunit beta,IL-2R subunit beta,IL-2RB,High affinity IL-2 receptor subunit beta,Interleukin-15 receptor subunit beta,p70-75 (p75),IL15RB,IL2RB
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宿主来源
Mouse抗原名称
CD122分子别名
Interleukin-2 receptor subunit beta; IL-2 receptor subunit beta; IL-2R subunit beta; IL-2RB; High affinity IL-2 receptor subunit beta; Interleukin-15 receptor subunit beta; p70-75 (p75); IL15RB; IL2RB细胞定位
Cell membraneAccession
P14784克隆号
S-2880抗体类型
Mouse mAb抗体同种型
IgG1,k反应种属 ?
Hu阳性样本
Human PBMC纯化方式
Protein G浓度
0.2 mg/ml标记
Biotin性状
Liquid缓冲体系
PBS pH7.4, 0.09% sodium azide
储存条件
12 months from date of receipt / reconstitution, 2 to 8 °C as supplied
应用
FCM
稀释度
应用 稀释度 推荐种属 FCM 5μl per million cells in 100μl volume Hu
CD122, also known as the interleukin-2 receptor beta (IL-2Rβ), is a key component of the IL-2 receptor complex and plays a crucial role in regulating immune responses. It is expressed on the surface of various immune cells, including T cells and natural killer (NK) cells. CD122 is involved in mediating the effects of IL-2, which is essential for the proliferation and differentiation of T cells, as well as the maintenance of regulatory T cells (Tregs). Recent studies have shown that targeting CD122 with selective IL-2 complexes can reduce immunosuppression by Tregs and enhance antitumor immunity, making it a promising target for cancer immunotherapy.
流式分析
Flow cytometric analysis of CD122 expression on human PBMC. Human PBMC were stained with PE Mouse Anti-Human CD56 Antibody and either Biotin Mouse IgG1, k Isotype Control (left panel) or SDT Biotin Mouse Anti-Human CD122 Antibody (right panel) at 5 μl/test followed by Sav-APC. Flow cytometry and data analysis were performed using BD FACSymphony™ A1 and FlowJo™ software.
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