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宿主来源
Mouse抗原名称
CD360分子别名
Interleukin-21 receptor; IL-21 receptor; IL-21R; Novel interleukin receptor; NILR; IL21R细胞定位
MembraneAccession
Q9HBE5克隆号
S-3285抗体类型
Mouse mAb抗体同种型
IgG1,k同型对照
S0B1519反应种属 ?
Hu阳性样本
Human PBMC纯化方式
Protein G浓度
0.2 mg/ml标记
Alexa Fluor® 488性状
Liquid缓冲体系
PBS, 1% BSA, 0.09% sodium azide
储存条件
12 months from date of receipt / reconstitution, 2 to 8 °C as supplied
应用
FCM
稀释度
应用 稀释度 推荐种属 FCM 5μl per million cells in 100μl volume Hu
The CD360 protein, also known as the B-cell receptor CD360 or Leukocyte Immunoglobulin-Like Receptor B1 (LILRB1), is an inhibitory receptor primarily expressed on the surface of immune cells such as B cells, monocytes, dendritic cells, and NK cells. Belonging to the Leukocyte Immunoglobulin-Like Receptor (LILR) family, it recognizes ligands like MHC class I molecules (e.g., HLA-G) and transmits inhibitory signals, thereby negatively regulating immune responses. It plays a critical role in maintaining immune homeostasis, preventing excessive activation, and mediating immune escape. Dysregulation of its function is closely associated with autoimmune diseases, infections, and tumor immune evasion, making it a potential target for immunotherapy research.
流式分析
Flow cytometric analysis of CD360 expression on human PBMC (human peripheral blood mononuclear cell). Human PBMC were stained with Brilliant Violet 421™ Mouse Anti-Human CD19 Antibody and either Alexa Fluor® 488 Mouse IgG1, k Isotype Control (left panel) or Alexa Fluor® 488 Mouse Anti-Human CD360 Antibody (right panel) at 5 μl/test. Flow cytometry and data analysis were performed using BD FACSymphony™ A1 and FlowJo™ software.
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