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宿主来源
Mouse抗原名称
CD42a分子别名
Platelet glycoprotein IX; GP-IX; GPIX; Glycoprotein 9; GP9细胞定位
MembraneAccession
P14770克隆号
S-4391抗体类型
Mouse mAb抗体同种型
IgG1,k反应种属 ?
Hu阳性样本
Fresh human peripheral blood cells纯化方式
Protein G浓度
0.2 mg/ml标记
PerCP-Cy5.5性状
Liquid缓冲体系
PBS, 1% BSA, 0.3% Proclin 300
储存条件
12 months from date of receipt / reconstitution, 2 to 8 °C as supplied
应用
FCM
稀释度
应用 稀释度 推荐种属 FCM 5μl per million cells in 100μl volume Hu
CD42a, also known as glycoprotein IX (GPIX), is a small, single-pass transmembrane glycoprotein expressed on platelets and megakaryocytes that non-covalently associates with glycoproteins Ibα, Ibβ, and V to form the GPIb-V-IX complex, which acts as the platelet receptor for von Willebrand factor (vWF), enabling vWF-dependent platelet adhesion to injured vessel walls and initiating arterial hemostasis; CD42a contains leucine-rich repeats, is encoded by GP9 on chromosome 3q21.3, and mutations in this gene cause Bernard–Soulier syndrome, a bleeding disorder characterized by giant platelets and impaired aggregation.
流式分析
Flow cytometric analysis of human CD42a expression on fresh human peripheral blood cells. Fresh human peripheral blood cells were stained with FITC Mouse Anti-Human CD41a Antibody and either PerCP-Cy5.5 Mouse IgG1, κ Isotype Control (left panel) or SDT PerCP-Cy5.5 Mouse Anti-Human CD42a Antibody (right panel) at 5 μl/test. Flow cytometry and data analysis were performed using BD FACSymphony™ A1 and FlowJo™ software.
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