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Biotin Mouse Anti-Human CD166 Antibody (S-2869)

CD166 antigen,Activated leukocyte cell adhesion molecule,MEMD,ALCAM

价格 1,000.00 供应商现货 : 3-5个工作日
货号 S0B80211
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产品规格
  • 宿主来源

    Mouse
  • 抗原名称

    CD166
  • 分子别名

    CD166 antigen; Activated leukocyte cell adhesion molecule; MEMD; ALCAM
  • 细胞定位

    Cell membrane
  • Accession

    Q13740
  • 克隆号

    S-2869
  • 抗体类型

    Mouse mAb
  • 抗体同种型

    IgG1,k
  • 反应种属 ?

    Hu
  • 阳性样本

    Human PBMC
  • 纯化方式

    Protein G
  • 浓度

    0.2 mg/ml
  • 标记

    Biotin
  • 性状

    Liquid
  • 缓冲体系

    PBS pH7.4, 0.03% Proclin 300

  • 储存条件

    12 months from date of receipt / reconstitution, 2 to 8 °C as supplied

  • 应用

    FCM

  • 稀释度

    应用 稀释度 推荐种属
    FCM 5μl per million cells in 100μl volume Hu
背景介绍
  • CD166, also known as Activated Leukocyte Cell Adhesion Molecule (ALCAM), is a type I transmembrane glycoprotein belonging to the immunoglobulin superfamily. It is encoded by the ALCAM gene and is involved in both homotypic and heterotypic cell adhesion. CD166 is expressed on various cell types, including activated T cells, epithelial cells, fibroblasts, and neurons. It plays a crucial role in mediating adhesion interactions between thymic epithelial cells and CD6+ cells during T cell development. Additionally, CD166 is overexpressed in several types of tumors and serves as a potential cancer stem cell marker, making it a target for cancer research and therapy.

  • 流式分析

    • Flow cytometric analysis of human CD166 expression on human PBMC (human peripheral blood mononuclear cell). Human PBMC were stained with Brilliant Violet 510™ Mouse Anti-Human CD14 Antibody and either Biotin Mouse IgG1, κ Isotype Control (left panel) or SDT Biotin Mouse Anti-Human CD166 Antibody (right panel) at 5 μl/test followed by Sav-APC. Flow cytometry and data analysis were performed using BD FACSymphony™ A1 and FlowJo™ software.

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