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宿主来源
Armenian hamster抗原名称
CD29分子别名
Integrin beta-1; Fibronectin receptor subunit beta; VLA-4 subunit beta; Itgb1细胞定位
Cell membrane, EndosomeAccession
P09055, P49134克隆号
HMB1-1抗体类型
Recombinant mAb抗体同种型
IgG反应种属 ?
Ms, Rt阳性样本
C57BL/6 mouse bone marrow纯化方式
Protein G浓度
0.5 mg/ml标记
Biotin性状
Liquid缓冲体系
PBS pH7.4, 0.03% Proclin 300
储存条件
12 months from date of receipt / reconstitution, 2 to 8 °C as supplied
应用
FCM
稀释度
应用 稀释度 推荐种属 FCM 1μg per million cells in 100μl volume Ms, Rt
CD29, also known as integrin beta-1 (ITGB1), is a crucial cell surface receptor involved in cell adhesion, migration, and signaling. It is a member of the integrin family and is encoded by the ITGB1 gene, located on human chromosome 10p11.2. CD29 forms complexes with various integrin alpha subunits to interact with extracellular matrix (ECM) proteins such as collagen, laminin, and fibronectin. This protein plays a significant role in cellular processes including “inside-out” and “outside-in” signaling pathways, which are essential for cell survival and metastasis. Additionally, CD29 is highly expressed in various cell types and is implicated in multiple diseases, including cancer progression and immune regulation.
流式分析
Flow cytometric analysis of CD29 expression on C57BL/6 mouse bone marrow. C57BL/6 mouse bone marrow was stained with Alexa Fluor® 647 Rat Anti-Mouse CD45R/B220 Antibody and either Biotin Armenian hamster IgG Isotype Control (left panel) or SDT Biotin Armenian hamster Anti-Mouse/Rat CD29 Antibody (right panel) at 2 μl/test followed by Sav-iFluor 488. Flow cytometry and data analysis were performed using Agilent NovoCyte Quanteon and FlowJo™ software.
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