分享产品介绍 评论(0)
宿主来源
Mouse抗原名称
CD44分子别名
CD44 antigen; Extracellular matrix receptor III (ECMR-III); GP90 lymphocyte homing/adhesion receptor; HUTCH-I; Hermes antigen; Hyaluronate receptor; Cd44细胞定位
Secreted, Cell membraneAccession
P26051克隆号
S-R623抗体类型
Mouse mAb抗体同种型
IgG2a,k反应种属 ?
Rt阳性样本
SD Rat splenocytes纯化方式
Protein A浓度
0.5 mg/ml标记
Biotin性状
Liquid缓冲体系
PBS pH7.4, 0.03% Proclin 300
储存条件
12 months from date of receipt / reconstitution, 2 to 8 °C as supplied
应用
FCM
稀释度
应用 稀释度 推荐种属 FCM 1μg per million cells in 100μl volume Rt
CD44H, also termed CD44s or the “standard/hematopoietic” isoform, is the smallest CD44 splice variant (≈37 kDa core, 80–95 kDa fully glycosylated) that lacks all variably spliced exons and functions as the cell’s dominant hyaluronan receptor, orchestrating hematopoietic progenitor trafficking, T-cell activation, angiogenesis, and tumor metastasis by coupling extracellular matrix adhesion to cytoskeletal signaling through its cytoplasmic tail-ERM-actin linkage and by serving as a membrane scaffold for metalloproteinases and growth-factor presentation.
流式分析
Flow cytometric analysis of rat CD44 expression on SD Rat splenocytes. SD Rat splenocytes were stained with PE Mouse Anti-Rat CD3 Antibody and either Biotin Mouse IgG2a, k Isotype Control (left panel) or SDT Biotin Mouse Anti-Rat CD44 Antibody (right panel) at 2 μl/test followed by Sav-iFluor 488. Flow cytometry and data analysis were performed using BD FACSymphony™ A1 and FlowJo™ software.
评论(0)