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宿主来源
Armenian hamster抗原名称
TCR Vγ2细胞定位
Cell membraneAccession
A2J008克隆号
UC3-10A6抗体类型
Recombinant mAb抗体同种型
IgG反应种属 ?
Ms阳性样本
C57BL/6 mouse splenocytes纯化方式
Protein G浓度
0.5 mg/ml标记
Biotin性状
Liquid缓冲体系
PBS pH7.4, 0.03% Proclin 300
储存条件
12 months from date of receipt / reconstitution, 2 to 8 °C as supplied
应用
FCM
稀释度
应用 稀释度 推荐种属 FCM 1μg per million cells in 100μl volume Ms
TCR Vγ2 protein is a variable-region subunit of the T-cell receptor (TCR) γ-chain that pairs with Vδ2 to form the predominant γδ TCR in human peripheral blood; this 280-residue Ig-like domain anchors to the γ-chain constant region, contacts antigen directly via surface-exposed CDR loops, and—when co-expressed with CD3 complexes—enables γδ T cells to sense phosphoantigens from microbes or stressed tumors without MHC restriction, triggering potent cytotoxicity and cytokine release that are being exploited for Vγ2/Vδ2-targeted immunotherapies against infection and cancer.
流式分析
Flow cytometric analysis of mouse TCR Vγ2 expression on C57BL/6 mouse splenocytes. C57BL/6 mouse splenocytes were stained with Brilliant Violet 421™ Rat Anti-Mouse CD3 Antibody and either Biotin Armenian hamster IgG Isotype Control (left panel) or SDT Biotin Armenian hamster Anti-Mouse TCR Vγ2 Antibody (right panel) at 2 μl/test followed by Sav-PE. Flow cytometry and data analysis were performed using Agilent NovoCyte Quanteon and FlowJo™ software.
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