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宿主来源
Rabbit抗原名称
CD44分子别名
CD44 antigen; CDw44; Epican; Extracellular matrix receptor III (ECMR-III); GP90 lymphocyte homing/adhesion receptor; HUTCH-I; LHR; MDU2; MDU3; MIC4免疫原
Recombinant Protein细胞定位
Cell membraneAccession
P16070克隆号
S-944-25抗体类型
Recombinant mAb抗体同种型
IgG反应种属 ?
Hu阳性样本
A431纯化方式
Protein A浓度
0.2 mg/ml标记
Pacific Blue性状
Liquid缓冲体系
PBS, 1% BSA, 0.3% Proclin 300
储存条件
12 months from date of receipt / reconstitution, 2 to 8 °C as supplied
应用
FCM
稀释度
应用 稀释度 推荐种属 FCM 5μl per million cells in 100μl volume Hu
CD44 is a multifunctional transmembrane glycoprotein that functions as a major adhesion molecule for hyaluronan and other extracellular matrix components, playing critical roles in cell migration, proliferation, differentiation, and survival; it is expressed in numerous isoforms generated through alternative splicing, with its standard form (CD44s) and variant isoforms (CD44v) exhibiting distinct tissue distributions and functional properties, and its dysregulated expression has been implicated in various pathological processes including inflammation, autoimmune diseases, and cancer progression where it contributes to tumor cell invasion, metastasis, and resistance to apoptosis.
流式分析
Flow cytometric analysis of Raji (Human Burkitt's lymphoma B lymphocyte, left) / A431 (Human epidermoid carcinoma epithelial cell, right) stained with Pacific Blue™ Mouse IgG Isotype Control (black line histogram) and SDT Pacific Blue™ Rabbit Anti-Human CD44 Antibody (red line histogram) at 5 μl/test. Cells without incubation with primary antibody and secondary antibody (blue line histogram) was used as unlabeled control. Flow cytometry and data analysis were performed using BD FACSymphony™ A1 and FlowJo™ software.
Negative control: Raji
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