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产品中心 抗体 Biosimilar抗体

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Anti-CD49d Monoclonal Antibody (Natalizumab)

价格 ￥1,800.00 （ 供应商现货 ： 3-5个工作日）
货号 S0B7126
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产品介绍

产品介绍 评论(0)

产品规格

  • 宿主来源

    Human

  • 抗原名称

    Integrin alpha-4

  • Accession

    P13612

  • 克隆号

    S-SC023

  • 抗体类型

    Recombinant mAb

  • 抗体同种型

    IgG4,k

  • 纯化方式

    Protein A

  • 浓度

    2 mg/ml

  • 内毒素含量

    <1EU/mg

  • 标记

    Unconjugated

  • 性状

    Liquid

  • 缓冲体系

    PBS pH7.4, containing no preservative

  • 储存条件

    12 months from date of receipt / reconstitution, 2 to 8 °C as supplied

  • 应用

    Blocking of Integrin alpha-4 signaling Functional assays

背景介绍

  • Natalizumab, is a monoclonal antibody which targets a protein called α4β1 integrin on white blood cells involved in inflammation. By attaching to integrin, natalizumab is thought to stop white blood cells from entering the brain and spinal cord tissue, thereby reducing inflammation and the resulting nerve damage.

  • 流式分析

    • Flow cytometric analysis of human peripheral blood leukocytes labelling Integrin alpha-4 antibody at 1μg / (Right panel) compared with a Human IgG Isotype Control / (Left panel). Goat Anti-Human IgG Alexa Fluor® 488 was used as the secondary antibody.

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