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宿主来源
Armenian hamster抗原名称
TCR Vγ2细胞定位
Cell membraneAccession
A2J008克隆号
UC3-10A6抗体类型
Recombinant mAb抗体同种型
Armenian hamster IgG同型对照
Invivo Armenian Hamster IgG Isotype Control反应种属 ?
Ms阳性样本
C57BL/6 mouse splenocytes纯化方式
Protein G浓度
5 mg/ml纯度
>95%(Determined by SDS-PAGE)内毒素含量
<1EU/mg标记
Unconjugated性状
Liquid缓冲体系
PBS pH7.4, Contains no stabilizers or preservatives
储存条件
2 to 8 °C for 2 weeks under sterile conditions;
-20 °C for 3 months under sterile conditions;
-80 °C for 24 months under sterile conditions.
Please avoid repeated freeze-thaw cycles.应用
in vivo cell specific depletion
FCM
稀释度
应用 稀释度 推荐种属 FCM 1:5000 Ms
TCR Vγ2 protein is a variable-region subunit of the T-cell receptor (TCR) γ-chain that pairs with Vδ2 to form the predominant γδ TCR in human peripheral blood; this 280-residue Ig-like domain anchors to the γ-chain constant region, contacts antigen directly via surface-exposed CDR loops, and—when co-expressed with CD3 complexes—enables γδ T cells to sense phosphoantigens from microbes or stressed tumors without MHC restriction, triggering potent cytotoxicity and cytokine release that are being exploited for Vγ2/Vδ2-targeted immunotherapies against infection and cancer.
流式分析
Flow cytometric analysis of C57BL/6 mouse splenocytes labeled with anti-mouse TCR Vγ2 antibody at 1/5000 dilution (0.1 μg) (right panel) compared to an Armenian hamster IgG Isotype Control (left panel). Goat Anti- Armenian hamster IgG Alexa Fluor® 488 was used as the secondary antibody. Then cells were stained with CD3 - Brilliant Violet 421™ antibody separately. Flow cytometry and data analysis were performed using Agilent NovoCyte Quanteon and FlowJo™ software.
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