Invivo anti-Mouse CD38 Recombinant mAb
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1,2'-phospho-ADP-ribosyl cyclase,2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase,2'-phospho-cyclic-ADP-ribose transferase,ADP-ribosyl cyclase 1 (ADPRC 1),Cyclic ADP-ribose hydrolase 1 (cADPR hydrolase 1),Cd38
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宿主来源
Rat抗原名称
CD38分子别名
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1; 2'-phospho-ADP-ribosyl cyclase; 2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase; 2'-phospho-cyclic-ADP-ribose transferase; ADP-ribosyl cyclase 1 (ADPRC 1); Cyclic ADP-ribose hydrolase 1 (cADPR hydrolase 1); Cd38细胞定位
MembraneAccession
P56528克隆号
NIMR5抗体类型
Rat mAb抗体同种型
Rat IgG2a,k同型对照
Invivo rat IgG2a isotype control, anti-trinitrophenol反应种属 ?
Ms阳性样本
C57BL/6 mouse splenocytes纯化方式
Protein G浓度
5 mg/ml纯度
>95% (Determined by SDS-PAGE)内毒素含量
<1EU/mg标记
Unconjugated性状
Liquid缓冲体系
PBS pH7.4, containing no preservative
储存条件
2 to 8 °C for 2 weeks under sterile conditions;
-20 °C for 3 months under sterile conditions;
-80 °C for 24 months under sterile conditions.
Please avoid repeated freeze-thaw cycles.应用
in vivo CD38 stimulation
in vitro CD38 stimulation
FCM
稀释度
应用 稀释度 推荐种属 FCM 1:500 Ms
CD38 is a multifunctional type II transmembrane glycoprotein expressed on immune cells and in various tissues, acting both as a receptor and an enzyme that converts NAD⁺ into cyclic ADP-ribose and ADP-ribose to regulate intracellular calcium signaling, immune cell activation, proliferation, and migration, and is also a key therapeutic target in multiple myeloma due to its high expression on malignant plasma cells and its role in modulating NAD⁺ levels linked to aging and metabolic processes.
流式分析
Flow cytometric analysis of Mouse CD38 expression on C57BL/6 mouse splenocytes. C57BL/6 mouse splenocytes were labeled with either Rat IgG2a Isotype Control (black line histogram) or SDT Rat Anti-Mouse CD38 antibody (red line histogram) at 1/500 dilution (1 μg). Goat Anti-Rat IgG Alexa Fluor® 488 was used as the secondary antibody. Flow cytometry and data analysis were performed using Agilent NovoCyte Quanteon and FlowJo™ software.
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