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产品中心 抗体 功能性抗体

Invivo Anti-Human CD54 (ICAM-1) Recombinant mAb

Intercellular adhesion molecule 1,Major group rhinovirus receptor,ICAM1

价格 ￥1,050.00 （ 供应商现货 ： 3-5个工作日）
货号 S0B7033
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产品介绍

产品介绍 评论(0)

产品规格

  • 宿主来源

    Mouse

  • 抗原名称

    ICAM-1/CD54

  • 分子别名

    Intercellular adhesion molecule 1; Major group rhinovirus receptor; ICAM1

  • 细胞定位

    Membrane

  • Accession

    P05362

  • 克隆号

    R6-5-D6

  • 抗体类型

    Mouse mAb

  • 抗体同种型

    IgG2a

  • 同型对照

    Invivo mouse IgG2a isotype control

  • 反应种属 ?

    Hu

  • 纯化方式

    Protein A

  • 浓度

    5 mg/ml

  • 纯度

    >95%(Determined by SDS-PAGE)

  • 内毒素含量

    <1EU/mg

  • 标记

    Unconjugated

  • 性状

    Liquid

  • 缓冲体系

    PBS pH7.4, containing no preservative

  • 储存条件

    2 to 8 °C for 2 weeks under sterile conditions;
    -20 °C for 3 months under sterile conditions;
    -80 °C for 24 months under sterile conditions.
    Please avoid repeated freeze-thaw cycles.

  • 应用

    in vitro T cell stimulation/activation

背景介绍

  • ICAM-1/CD54 is an 85–110 kDa transmembrane glycoprotein of the immunoglobulin superfamily that is expressed on endothelial, epithelial and immune cells; upon binding its ligands LFA-1 (CD11a/CD18) and Mac-1 (CD11b/CD18) it serves as the critical adhesion checkpoint that promotes firm leukocyte arrest on the vessel wall, enables subsequent diapedesis into inflamed tissue, and amplifies antigen-specific T-cell activation, thereby positioning it at the mechanistic center of inflammatory, autoimmune and anti-tumor immune responses.

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