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Invivo anti-mouse CD16/CD32 Recombinant mAb

价格 ￥700.00 （ 供应商现货 ： 3-5个工作日）
货号 S0B7003
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产品介绍

产品介绍 评论(0)

产品规格

  • 宿主来源

    Rat

  • 抗原名称

    CD16/CD32

  • Accession

    P08508, P08101

  • 克隆号

    2.4G2

  • 抗体类型

    Rat mAb

  • 抗体同种型

    IgG2b,κ

  • 同型对照

    Invivo rat IgG2b isotype control, anti-keyhole limpet hemocyanin

  • 反应种属 ?

    Ms

  • 纯化方式

    Protein G

  • 浓度

    5 mg/ml

  • 纯度

    >95% (Determined by SDS-PAGE)

  • 标记

    Unconjugated

  • 性状

    Liquid

  • 缓冲体系

    PBS pH7.4

  • 储存条件

    2 to 8 °C for 2 weeks under sterile conditions;
    -20 °C for 3 months under sterile conditions;
    -80 °C for 24 months under sterile conditions.
    Please avoid repeated freeze-thaw cycles.

  • 应用

    in vivo Fc receptor blocking

背景介绍

  • This antibody recognizes the same epitope as clone 2.4G2. All of the Fcγ receptors (FcγR) belong to the immunoglobulin superfamily and are the most important Fc receptors for inducing phagocytosis of opsonized (marked) microbes. This family includes several members, FcγRI (CD64), FcγRIIA (CD32), FcγRIIB (CD32), FcγRIIIA (CD16a), FcγRIIIB (CD16b), which differ in their antibody affinities due to their different molecular structure. CD16/CD32 are expressed on natural killer cells, monocytes, macrophages, dendritic cells (at low levels), Kupffer cells, granulocytes, mast cells, B lymphocytes, immature thymocytes, and some activated mature T lymphocytes.

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