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Rat抗原名称
CD49B分子别名
Integrin alpha-2; CD49 antigen-like family member B; Collagen receptor; Platelet membrane glycoprotein Ia (GPIa); VLA-2 subunit alpha; ITGA2免疫原
Recombinant Protein细胞定位
MembraneAccession
P17301克隆号
S-1969-12抗体类型
Rat mAb反应种属 ?
Hu, Ms阳性样本
A431, mouse spleen纯化方式
Protein G浓度
2 mg/ml标记
Unconjugated性状
Liquid缓冲体系
PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300
储存条件
12 months from date of receipt / reconstitution, -20 °C as supplied
应用
WB
稀释度
应用 稀释度 推荐种属 WB 1:1000 Hu, Ms
CD49b, also known as the integrin alpha-2 subunit (ITGA2), is a transmembrane glycoprotein that primarily associates with CD29 (integrin beta-1) to form the VLA-2 complex, serving as a key cell surface receptor for collagen and laminin. Widely expressed on platelets, epithelial cells, fibroblasts, and specific immune subsets such as NK cells and T cells, it plays a central role in mediating cell adhesion, migration, signal transduction, and platelet activation; furthermore, it is deeply involved in pathological processes including tissue repair, angiogenesis, and tumor metastasis, acting as a critical bridge connecting the extracellular matrix to the intracellular cytoskeleton.
免疫印迹
WB result of CD49B Recombinant Rat mAb
Primary antibody: CD49B Recombinant Rat mAb at 1/1000 dilution
Lane 1: MCF7 whole cell lysate 20 µg
Lane 2: A431 whole cell lysate 20 µg
Low expression control: MCF7 whole cell lysate
Secondary antibody: Goat Anti- rat IgG, (H+L), HRP conjugated at 1/10000 dilution
Predicted MW: 129 kDa
Observed MW: 150 kDaWB result of CD49B Recombinant Rat mAb
Primary antibody: CD49B Recombinant Rat mAb at 1/1000 dilution
Lane 1: mouse spleen lysate 20 µg
Secondary antibody: Goat Anti- rat IgG, (H+L), HRP conjugated at 1/10000 dilution
Predicted MW: 129 kDa
Observed MW: 150 kDa
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