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PCBP4 Recombinant Rabbit mAb (S-3107-175)

Poly(rC)-binding protein 4

价格 ￥600.00 （ 供应商现货 ： 3-5个工作日）
货号 S0B6748
规格
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产品介绍

产品介绍 评论(0)

产品规格

  • 宿主来源

    Rabbit

  • 抗原名称

    PCBP4

  • 分子别名

    Poly(rC)-binding protein 4

  • 免疫原

    Synthetic Peptide

  • 细胞定位

    Cytoplasm

  • Accession

    P57723

  • 克隆号

    S-3107-175

  • 抗体类型

    Recombinant mAb

  • 抗体同种型

    IgG

  • 反应种属 ?

    Hu, Ms, Rt, Mk

  • 阳性样本

    HeLa, NIH/3T3, PC-12, COS-7

  • 纯化方式

    Protein A

  • 浓度

    2 mg/ml

  • 标记

    Unconjugated

  • 性状

    Liquid

  • 缓冲体系

    PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300

  • 储存条件

    12 months from date of receipt / reconstitution, -20 °C as supplied

  • 应用

    WB

  • 稀释度

    应用 稀释度 推荐种属
    WB 1:1000 Hu, Ms, Rt, Mk
背景介绍

  • PCBP4 (Poly(rC) Binding Protein 4), also known as MCG10 or hnRNP E4, is an RNA-binding protein belonging to the hnRNP K homology domain-containing family. It regulates mRNA stability, translation, and alternative splicing by binding to poly(C) motifs in target transcripts. PCBP4 plays critical roles in cellular stress responses, cell cycle arrest, and apoptosis through post-transcriptional control of genes involved in proliferation and DNA damage response. Its expression is frequently downregulated in various cancers, functioning as a tumor suppressor by stabilizing mRNAs encoding cell cycle inhibitors and pro-apoptotic factors.

  • 免疫印迹

    • WB result of PCBP4 Recombinant Rabbit mAb
      Primary antibody: PCBP4 Recombinant Rabbit mAb at 1/1000 dilution
      Lane 1: HL-60 whole cell lysate 20 µg
      Lane 2: HeLa whole cell lysate 20 µg
      Negative control: HL-60 whole cell lysate
      Secondary antibody: Goat Anti- rabbit IgG, (H+L), HRP conjugated at 1/10000 dilution
      Predicted MW: 41 kDa
      Observed MW: 41 kDa
      This blot was developed with high sensitivity substrate

    • WB result of PCBP4 Recombinant Rabbit mAb
      Primary antibody: PCBP4 Recombinant Rabbit mAb at 1/1000 dilution
      Lane 1: NIH/3T3 whole cell lysate 20 µg
      Secondary antibody: Goat Anti- rabbit IgG, (H+L), HRP conjugated at 1/10000 dilution
      Predicted MW: 41 kDa
      Observed MW: 41 kDa
      This blot was developed with high sensitivity substrate

    • WB result of PCBP4 Recombinant Rabbit mAb
      Primary antibody: PCBP4 Recombinant Rabbit mAb at 1/1000 dilution
      Lane 1: PC-12 whole cell lysate 20 µg
      Secondary antibody: Goat Anti- rabbit IgG, (H+L), HRP conjugated at 1/10000 dilution
      Predicted MW: 41 kDa
      Observed MW: 41 kDa
      This blot was developed with high sensitivity substrate

    • WB result of PCBP4 Recombinant Rabbit mAb
      Primary antibody: PCBP4 Recombinant Rabbit mAb at 1/1000 dilution
      Lane 1: COS-7 whole cell lysate 20 µg
      Secondary antibody: Goat Anti- rabbit IgG, (H+L), HRP conjugated at 1/10000 dilution
      Predicted MW: 41 kDa
      Observed MW: 41 kDa
      This blot was developed with high sensitivity substrate

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