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宿主来源
Rabbit抗原名称
OX40L分子别名
Tumor necrosis factor ligand superfamily member 4; Glycoprotein Gp34; OX40 ligand (OX40L); TAX transcriptionally-activated glycoprotein 1; CD252; TXGP1; TNFSF4免疫原
Synthetic Peptide细胞定位
MembraneAccession
P23510克隆号
S-2597-17抗体类型
Recombinant mAb抗体同种型
IgG反应种属 ?
Hu阳性样本
HUVEC纯化方式
Protein A浓度
0.5 mg/ml标记
Unconjugated性状
Liquid缓冲体系
PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300
储存条件
12 months from date of receipt / reconstitution, -20 °C as supplied
应用
WB
稀释度
应用 稀释度 推荐种属 WB 1:1000 Hu
OX40L (also called CD252 or TNFSF4) is a type-II transmembrane glycoprotein of the TNF superfamily that is chiefly expressed on antigen-presenting cells such as dendritic cells, B cells and macrophages; when it engages its receptor OX40 (CD134) on recently activated CD4⁺ and CD8⁺ T cells it delivers a potent co-stimulatory signal that triggers TRAF-dependent cascades (PI3K–Akt, NF-κB1), thereby amplifying T-cell proliferation, survival, cytokine secretion and memory formation, a mechanism exploited experimentally by OX40L agonists to boost anti-tumor immunity and targeted therapeutically by blocking agents to dampen harmful inflammation in autoimmunity and allergic diseases.
免疫印迹
WB result of OX40L Recombinant Rabbit mAb
Primary antibody: OX40L Recombinant Rabbit mAb at 1/1000 dilution
Lane 1: HeLa whole cell lysate 20 µg
Lane 2: HUVEC whole cell lysate 20 µg
Negative control: HeLa whole cell lysate
Secondary antibody: Goat Anti-Rabbit IgG, (H+L), HRP conjugated at 1/10000 dilution Predicted MW: 21 kDa
Observed MW: 30 kDaWB result of OX40L Recombinant Rabbit mAb
Primary antibody: OX40L Recombinant Rabbit mAb at 1/1000 dilution
Lane 1: OX40L protein 1 ng
Secondary antibody: Goat Anti-Rabbit IgG, (H+L), HRP conjugated at 1/10000 dilution Predicted MW: 21 kDa
Observed MW: 23 kDa
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