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Rabbit抗原名称
KLK6分子别名
Kallikrein-6; Neurosin; Protease M; SP59; Serine protease 18; Serine protease 9; Zyme; PRSS18; PRSS9免疫原
Synthetic Peptide细胞定位
Secreted, Mitochondrion, Endoplasmic reticulum, Cytoplasm, NucleusAccession
Q92876克隆号
S-2492-111抗体类型
Recombinant mAb抗体同种型
IgG反应种属 ?
Hu阳性样本
TE-1, HT-29纯化方式
Protein A浓度
0.5 mg/ml标记
Unconjugated性状
Liquid缓冲体系
PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300
储存条件
12 months from date of receipt / reconstitution, -20 °C as supplied
应用
WB
稀释度
应用 稀释度 推荐种属 WB 1:1000 Hu
KLK6 (kallikrein-related peptidase 6) is a secreted serine protease encoded on chromosome 19q13.3–13.4 that exerts context-dependent regulation of tumor behavior by cleaving extracellular matrix proteins and activating protease-activated receptors, thereby promoting proliferation, migration, invasion, angiogenesis, and chemoresistance in gastric, colorectal, lung, bladder, and other cancers while also modulating epithelial-to-mesenchymal transition and macrophage–tumor crosstalk via PAR1/PAR2 signaling cascades, making its elevated expression a consistent biomarker of poor prognosis.
免疫印迹
WB result of KLK6 Recombinant Rabbit mAb
Primary antibody: KLK6 Recombinant Rabbit mAb at 1/1000 dilution
Lane 1: HeLa whole cell lysate 20 µg
Lane 2: U-2 OS whole cell lysate 20 µg
Lane 3: TE-1 whole cell lysate 20 µg
Lane 4: HT-29 whole cell lysate 20 µg
Negative control: HeLa whole cell lysate
Low expression control: U-2 OS whole cell lysate
Secondary antibody: Goat Anti- rabbit IgG, (H+L), HRP conjugated at 1/10000 dilution
Predicted MW: 27 kDa
Observed MW: 27 kDa
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