CD122 Recombinant Rabbit mAb (S-3364-9)
Interleukin-2 receptor subunit beta,IL-2 receptor subunit beta,IL-2R subunit beta,IL-2RB,High affinity IL-2 receptor subunit beta,Interleukin-15 receptor subunit betaImported,p70-75 (p75),IL15RB,IL2RB
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宿主来源
Rabbit抗原名称
CD122分子别名
Interleukin-2 receptor subunit beta; IL-2 receptor subunit beta; IL-2R subunit beta; IL-2RB; High affinity IL-2 receptor subunit beta; Interleukin-15 receptor subunit betaImported; p70-75 (p75); IL15RB; IL2RB免疫原
Recombinant Protein细胞定位
Cell membraneAccession
P14784克隆号
S-3364-9抗体类型
Recombinant mAb抗体同种型
IgG反应种属 ?
Hu阳性样本
NK-92, Karpas-299, HuT-78纯化方式
Protein A浓度
2 mg/ml标记
Unconjugated性状
Liquid缓冲体系
PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300
储存条件
12 months from date of receipt / reconstitution, -20 °C as supplied
应用
WB
稀释度
应用 稀释度 推荐种属 WB 1:1000 Hu
CD122, also known as the interleukin-2 receptor beta (IL-2Rβ), is a key component of the IL-2 receptor complex and plays a crucial role in regulating immune responses. It is expressed on the surface of various immune cells, including T cells and natural killer (NK) cells. CD122 is involved in mediating the effects of IL-2, which is essential for the proliferation and differentiation of T cells, as well as the maintenance of regulatory T cells (Tregs). Recent studies have shown that targeting CD122 with selective IL-2 complexes can reduce immunosuppression by Tregs and enhance antitumor immunity, making it a promising target for cancer immunotherapy.
免疫印迹
WB result of CD122 Recombinant Rabbit mAb
Primary antibody: CD122 Recombinant Rabbit mAb at 1/1000 dilution
Lane 1: Daudi whole cell lysate 20 µg
Lane 2: NK-92 whole cell lysate 20 µg
Lane 3: Karpas-299 whole cell lysate 20 µg
Lane 4: HuT-78 whole cell lysate 20 µg
Negative control: Daudi whole cell lysate
Secondary antibody: Goat Anti- rabbit IgG, (H+L), HRP conjugated at 1/10000 dilution
Predicted MW: 61 kDa
Observed MW: 75 kDa
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