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宿主来源
Rabbit抗原名称
IFN-γ克隆号
S-3623抗体类型
Recombinant mAb抗体同种型
IgG反应种属 ?
Rt纯化方式
Protein A浓度
0.5 mg/ml标记
Unconjugated性状
Liquid缓冲体系
PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300
储存条件
12 months from date of receipt / reconstitution, -20 °C as supplied
应用
ELISA
稀释度
应用 稀释度 推荐种属 ELISA 1:5000-1:10000 Rt
Rat IFN-γ (interferon-gamma) is a 15–16 kDa, 136-amino-acid type II cytokine secreted chiefly by activated NK cells and Th1-type CD4⁺ T cells. It signals through a high-affinity heterodimeric receptor composed of IFN-γR1/IFN-γR2, activating the JAK–STAT1 pathway to up-regulate MHC class I and II molecules, chemokines such as CXCL9/10, and multiple antimicrobial effectors. In rats this molecule is encoded by the Ifng gene on chromosome 7 and is heavily N-glycosylated; it functions as a non-covalent antiparallel dimer with species-specific biological activity that is essential for macrophage activation, Th1 polarization, and control of intracellular pathogens.
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