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宿主来源
Mouse克隆号
S-3646抗体类型
Recombinant mAb抗体同种型
IgG1反应种属 ?
Hu纯化方式
Protein G浓度
0.5 mg/ml标记
Unconjugated性状
Liquid缓冲体系
PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300
储存条件
12 months from date of receipt / reconstitution, -20 °C as supplied
应用
ELISA
稀释度
应用 稀释度 推荐种属 ELISA 1:5000-1:10000 Hu
Insulin-like growth factor 1 (IGF-1), also known as somatomedin C, is a peptide hormone composed of 70 amino acids with a molecular weight of approximately 7.6 kDa. It is primarily produced by the liver and regulated by growth hormone (GH), acting as the main mediator of GH's growth-promoting effects. IGF-1 circulates in the blood, bound to binding proteins that modulate its availability to tissues. It plays a crucial role in promoting cell growth, differentiation, and protein synthesis in various tissues, including muscle, bone, and cartilage. Additionally, IGF-1 has significant effects on brain development and is involved in the regulation of metabolism. Its levels can be used to assess GH status in medical contexts. IGF-1 is a versatile biomarker for diagnosing, monitoring, and managing endocrine (Growth Hormone Disorders), metabolic, oncological, cardiovascular, and neurological conditions. Its clinical application requires careful interpretation in context with patient-specific factors.
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