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宿主来源
Rabbit抗原名称
ADAMTS14分子别名
A disintegrin and metalloproteinase with thrombospondin motifs 14; ADAM-TS 14; ADAM-TS14; ADAMTS-14免疫原
Synthetic Peptide细胞定位
SecretedAccession
Q8WXS8克隆号
S-2935-69抗体类型
Recombinant mAb抗体同种型
IgG反应种属 ?
Hu纯化方式
Protein A浓度
0.5 mg/ml标记
Unconjugated性状
Liquid缓冲体系
PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300
储存条件
12 months from date of receipt / reconstitution, -20 °C as supplied
应用
WB
稀释度
应用 稀释度 推荐种属 WB 1:1000 Hu
ADAMTS14 is a secreted 1223-amino-acid member of the ADAMTS zinc metalloproteinase family that processes extracellular matrix components, displaying the signature architecture of a signal peptide, prodomain, peptidase M12B catalytic domain, disintegrin-like module, cysteine-rich spacer and four thrombospondin type-1 repeats followed by a PLAC domain; it is expressed in placenta, retina, lung and brain, cleaves the N-terminal propeptide of type I procollagen to facilitate collagen fibril formation, modulates TGF-β signaling and mesenchymal cell behavior, and genetically or expressionally altered ADAMTS14 has been linked to osteoarthritis, intervertebral disc degeneration, cancer progression, cardiovascular remodeling and pulmonary fibrosis.
免疫印迹
WB result of ADAMTS14 Recombinant Rabbit mAb
Primary antibody: ADAMTS14 Recombinant Rabbit mAb at 1/1000 dilution
Lane 1: 293F transfected with empty vector whole cell lysate 20 µg
Lane 2: 293F transfected with ADAMTS14-myc fusion protein whole cell lysate 20 µg
Secondary antibody: Goat Anti- rabbit IgG, (H+L), HRP conjugated at 1/10000 dilution
Predicted MW: 134 kDa
Observed MW: 134 kDa
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