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宿主来源
Rabbit抗原名称
NMDA Receptor 2A (GluN2A)分子别名
Glutamate receptor ionotropic, NMDA 2A; GluN2A; Glutamate [NMDA] receptor subunit epsilon-1; N-methyl D-aspartate receptor subtype 2A (NMDAR2A; NR2A; hNR2A); NMDAR2A; GRIN2A免疫原
Synthetic Peptide细胞定位
Cell membraneAccession
Q12879克隆号
S-2126-168抗体类型
Recombinant mAb抗体同种型
IgG反应种属 ?
Hu, Ms阳性样本
mouse brain纯化方式
Protein A浓度
0.5 mg/ml标记
Unconjugated性状
Liquid缓冲体系
PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300
储存条件
12 months from date of receipt / reconstitution, -20 °C as supplied
应用
WB
稀释度
应用 稀释度 推荐种属 WB 1:1000 Hu, Ms
NMDA Receptor 2A (GluN2A) is a critical subunit of the N-methyl-D-aspartate (NMDA) receptor, a subtype of ionotropic glutamate receptor that plays a pivotal role in synaptic plasticity, learning, and memory; GluN2A-containing receptors are highly expressed in the adult forebrain, exhibit faster kinetics and higher open probability than GluN2B-containing receptors, and their proper trafficking, phosphorylation, and interaction with scaffolding proteins such as PSD-95 are essential for regulating synaptic strength, with dysregulation or mutations in GRIN2A (the gene encoding GluN2A) linked to neurodevelopmental disorders including intellectual disability, epilepsy, and schizophrenia.
免疫印迹
WB result of NMDA Receptor 2A (GluN2A) Recombinant Rabbit mAb
Primary antibody: NMDA Receptor 2A (GluN2A) Recombinant Rabbit mAb at 1/1000 dilution
Lane 1: mouse heart lysate 20 µg
Lane 2: mouse brain lysate 20 µg
Negative control: mouse heart lysate
Secondary antibody: Goat Anti- rabbit IgG, (H+L), HRP conjugated at 1/10000 dilution
Predicted MW: 165 kDa
Observed MW: 180 kDa
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