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P2ry12 Recombinant Rabbit mAb (S-3134-73)

P2Y purinoceptor 12,P2Y12,ADP-glucose receptor (ADPG-R),P2T(AC),P2Y(AC),P2Y(cyc),P2Y12 platelet ADP receptor (P2Y(ADP)),SP1999,HORK3,P2RY12

价格 ￥600.00 （ 供应商现货 ： 3-5个工作日）
货号 S0B6568
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产品介绍

产品介绍 评论(0)

产品规格

  • 宿主来源

    Rabbit

  • 抗原名称

    P2ry12

  • 分子别名

    P2Y purinoceptor 12; P2Y12; ADP-glucose receptor (ADPG-R); P2T(AC); P2Y(AC); P2Y(cyc); P2Y12 platelet ADP receptor (P2Y(ADP)); SP1999; HORK3; P2RY12

  • 免疫原

    Synthetic Peptide

  • 细胞定位

    Cell membrane

  • Accession

    Q9H244

  • 克隆号

    S-3134-73

  • 抗体类型

    Recombinant mAb

  • 抗体同种型

    IgG

  • 反应种属 ?

    Hu, Ms, Rt

  • 阳性样本

    U-87 MG, IMR-32, A549, NIH/3T3, mouse heart, mouse brain, rat heart, rat brain, C6

  • 纯化方式

    Protein A

  • 浓度

    0.5 mg/ml

  • 标记

    Unconjugated

  • 性状

    Liquid

  • 缓冲体系

    PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300

  • 储存条件

    12 months from date of receipt / reconstitution, -20 °C as supplied

  • 应用

    ICC ?

    WB

  • 稀释度

    应用 稀释度 推荐种属
    WB 1:1000 Hu, Ms, Rt
背景介绍

  • P2RY12 (purinergic receptor P2Y, G-protein coupled, 12) is a 22 kDa Gαi-coupled seven-transmembrane receptor that is best known as the primary platelet receptor for ADP, where it triggers Rap1- and αIIbβ3 integrin-dependent aggregation and is the target of widely used antithrombotic drugs such as clopidogrel; beyond hemostasis, the same receptor is expressed on osteoclasts, microglia, vascular smooth-muscle cells and certain neurons, mediating ADP-evoked bone resorption, microglial chemotaxis and synaptic pruning, foam-cell formation in atherosclerosis, and neuroinflammatory responses that can either exacerbate or protect against neurodegeneration depending on context.

  • 免疫印迹

    • WB result of P2ry12 Recombinant Rabbit mAb
      Primary antibody: P2ry12 Recombinant Rabbit mAb at 1/1000 dilution
      Lane 1: U-87 MG whole cell lysate 20 µg
      Lane 2: IMR-32 whole cell lysate 20 µg
      Lane 3: A549 whole cell lysate 20 µg
      Secondary antibody: Goat Anti- rabbit IgG, (H+L), HRP conjugated at 1/10000 dilution
      Predicted MW: 39 kDa
      Observed MW: 50 kDa

    • WB result of P2ry12 Recombinant Rabbit mAb
      Primary antibody: P2ry12 Recombinant Rabbit mAb at 1/1000 dilution
      Lane 1: NIH/3T3 whole cell lysate 20 µg
      Lane 2: mouse heart lysate 20 µg
      Lane 3: mouse brain lysate 20 µg
      Secondary antibody: Goat Anti- rabbit IgG, (H+L), HRP conjugated at 1/10000 dilution
      Predicted MW: 39 kDa
      Observed MW: 50 kDa

    • WB result of P2ry12 Recombinant Rabbit mAb
      Primary antibody: P2ry12 Recombinant Rabbit mAb at 1/1000 dilution
      Lane 1: C6 whole cell lysate 20 µg
      Lane 2: rat heart lysate 20 µg
      Lane 3: rat brain lysate 20 µg
      Secondary antibody: Goat Anti- rabbit IgG, (H+L), HRP conjugated at 1/10000 dilution
      Predicted MW: 39 kDa
      Observed MW: 50 kDa

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