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Glutamate Receptor 1 Recombinant Rabbit mAb (S-1892-144)

GluR-1,AMPA-selective glutamate receptor 1,GluR-A,GluR-K1,Glutamate receptor ionotropic,AMPA 1,GLUA1,GLUH1,GLUR1,GRIA1

价格 ￥600.00 （ 供应商现货 ： 3-5个工作日）
货号 S0B6541
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产品介绍

产品介绍 评论(0)

产品规格

  • 宿主来源

    Rabbit

  • 抗原名称

    Glutamate Receptor 1

  • 分子别名

    GluR-1; AMPA-selective glutamate receptor 1; GluR-A; GluR-K1; Glutamate receptor ionotropic; AMPA 1; GLUA1; GLUH1; GLUR1; GRIA1

  • 免疫原

    Recombinant Protein

  • 细胞定位

    Cell membrane

  • Accession

    P42261

  • 克隆号

    S-1892-144

  • 抗体类型

    Recombinant mAb

  • 抗体同种型

    IgG

  • 反应种属 ?

    Ms, Rt

  • 阳性样本

    unboiled mouse brain, unboiled mouse cerebellum, unboiled rat brain, unboiled rat cerebellum

  • 预测反应种属
    (反应种属缩写表)

    Hu, CyMk

  • 纯化方式

    Protein A

  • 浓度

    0.5 mg/ml

  • 标记

    Unconjugated

  • 性状

    Liquid

  • 缓冲体系

    PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300

  • 储存条件

    12 months from date of receipt / reconstitution, -20 °C as supplied

  • 应用

    WB

  • 稀释度

    应用 稀释度 推荐种属
    WB 1:1000 Ms, Rt
背景介绍

  • Glutamate Receptor 1 (GluR1, also called GRIA1 or AMPA-R subunit 1) is a 906-aa transmembrane protein that assembles with other AMPA-type ionotropic glutamate-receptor subunits into Ca2+-permeable, fast-desensitizing ligand-gated channels that mediate the majority of rapid excitatory neurotransmission in the mammalian CNS; its cytoplasmic C-tail contains a PDZ-binding motif that docks PSD-95 family scaffolds and regulates activity-dependent phosphorylation (Ser831/Ser845) and membrane trafficking, thereby controlling synaptic strength, long-term potentiation, learning, memory, and pathological excitotoxicity in stroke, epilepsy, and neurodegeneration.

  • 免疫印迹

    • WB result of Glutamate Receptor 1 Recombinant Rabbit mAb
      Primary antibody: Glutamate Receptor 1 Recombinant Rabbit mAb at 1/1000 dilution
      Lane 1: unboiled mouse liver lysate 20 µg
      Lane 2: unboiled mouse brain lysate 20 µg
      Lane 3: unboiled mouse cerebellum lysate 20 µg
      Negative control: unboiled mouse liver lysate
      Secondary antibody: Goat Anti- rabbit IgG, (H+L), HRP conjugated at 1/10000 dilution
      Predicted MW: 102 kDa
      Observed MW: 110 kDa
      This blot was developed with high sensitivity substrate

    • WB result of Glutamate Receptor 1 Recombinant Rabbit mAb
      Primary antibody: Glutamate Receptor 1 Recombinant Rabbit mAb at 1/1000 dilution
      Lane 1: unboiled rat liver lysate 20 µg
      Lane 2: unboiled rat brain lysate 20 µg
      Lane 3: unboiled rat cerebellum lysate 20 µg
      Negative control: unboiled rat liver lysate
      Secondary antibody: Goat Anti- rabbit IgG, (H+L), HRP conjugated at 1/10000 dilution
      Predicted MW: 102 kDa
      Observed MW: 110 kDa

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