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宿主来源
Rabbit抗原名称
CD11c分子别名
Integrin alpha-X; CD11 antigen-like family member C; Leu M5; Leukocyte adhesion glycoprotein p150,95 alpha chain; Leukocyte adhesion receptor p150,95; CD11C; ITGAX细胞定位
MembraneAccession
P20702克隆号
S-3824抗体类型
Recombinant mAb抗体同种型
IgG反应种属 ?
Ms纯化方式
Protein A浓度
2 mg/ml标记
Unconjugated性状
Liquid缓冲体系
PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300
储存条件
12 months from date of receipt / reconstitution, -20 °C as supplied
应用
IHC-P ?
稀释度
应用 稀释度 推荐种属 IHC-P 1:250 Ms
CD11c is a type I transmembrane protein and a member of the β2 integrin family, primarily expressed on dendritic cells, monocytes, macrophages, neutrophils, and some B cells. It forms a heterodimer with CD18, known as integrin αXβ2. This molecule plays a crucial role in immune cell functions such as adhesion, phagocytosis, and cell migration. CD11c is also involved in the regulation of B cell homeostasis and the development of T cells in the thymus. Additionally, it has been implicated in the clearance of apoptotic cells by microglia during developmental apoptosis.
免疫组化
IHC shows positive staining in paraffin-embedded mouse spleen. Anti-CD11c antibody was used at 1/250 dilution, followed by a HRP Polymer for Mouse & Rabbit IgG (ready to use). Counterstained with hematoxylin. Heat mediated antigen retrieval with Tris/EDTA buffer pH9.0 was performed before commencing with IHC staining protocol.
组织表达图谱
Expression of CD11c in mouse & rat tissue.
FAQs
我们一般不推荐客户回收利用抗体。 因为抗体使用之后缓冲体系已经发生改变，不同客户在回收抗体的保存条件上也会有差异，所以抗体回收使用效果无法保证。另外，我们对一批抗体回收验证测试，测试结果显示不同抗体可回收次数不同，一般效价越高的抗体，可重复使用的次数越多，客户可根据实验情况来确定
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