RANKL Recombinant Rabbit mAb (S-2636-218)
Tumor necrosis factor ligand superfamily member 11,Osteoclast differentiation factor (ODF),Osteoprotegerin ligand (OPGL),Receptor activator of nuclear factor kappa-B ligand (RANKL),TNF-related activation-induced cytokine (TRANCE),CD254,OPGL,TRANCE,TNFSF11
分享产品介绍 FAQs 评论(0)
宿主来源
Rabbit抗原名称
RANKL分子别名
Tumor necrosis factor ligand superfamily member 11; Osteoclast differentiation factor (ODF); Osteoprotegerin ligand (OPGL); Receptor activator of nuclear factor kappa-B ligand (RANKL); TNF-related activation-induced cytokine (TRANCE); CD254; OPGL; TRANCE; TNFSF11免疫原
Recombinant Protein细胞定位
Cell membraneAccession
O14788克隆号
S-2636-218抗体类型
Recombinant mAb抗体同种型
IgG反应种属 ?
Hu阳性样本
Raji, THP-1, BxPC-3纯化方式
Protein A浓度
2 mg/ml标记
Unconjugated性状
Liquid缓冲体系
PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300
储存条件
12 months from date of receipt / reconstitution, -20 °C as supplied
应用
WB
稀释度
应用 稀释度 推荐种属 WB 1:1000 Hu
RANKL (Receptor Activator of Nuclear Factor Kappa-B Ligand), also known as TNFSF11, is a critical type II transmembrane protein belonging to the TNF superfamily that functions as the principal stimulatory factor for osteoclast formation, activation, and survival by binding to its receptor RANK on osteoclast precursor cells, thereby playing an essential role in bone remodeling, calcium metabolism, and immune responses, while its overexpression is implicated in various bone-related diseases such as osteoporosis, rheumatoid arthritis, and bone metastases, making it a key therapeutic target for denosumab and other RANKL inhibitors.
免疫印迹
WB result of RANKL Recombinant Rabbit mAb
Primary antibody: RANKL Recombinant Rabbit mAb at 1/1000 dilution
Lane 1: Raji whole cell lysate 20 µg
Lane 2: THP-1 whole cell lysate 20 µg
Lane 3: BxPC-3 whole cell lysate 20 µg
Secondary antibody: Goat Anti-rabbit IgG, (H+L), HRP conjugated at 1/10000 dilution
Predicted MW: 35 kDa
Observed MW: 37 kDa
This blot was developed with high sensitivity substrate
免疫细胞化学
FAQs
我们一般不推荐客户回收利用抗体。 因为抗体使用之后缓冲体系已经发生改变，不同客户在回收抗体的保存条件上也会有差异，所以抗体回收使用效果无法保证。另外，我们对一批抗体回收验证测试，测试结果显示不同抗体可回收次数不同，一般效价越高的抗体，可重复使用的次数越多，客户可根据实验情况来确定
评论(0)