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Gelsolin Rabbit Polyclonal Antibody

AGEL,Actin-depolymerizing factor (ADF),Brevin,GSN

价格 ￥400.00 （ 供应商现货 ： 3-5个工作日）
货号 S0B6353
规格
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产品介绍

产品介绍 FAQs 评论(0)

产品规格

  • 宿主来源

    Rabbit

  • 抗原名称

    Gelsolin

  • 分子别名

    AGEL; Actin-depolymerizing factor (ADF); Brevin; GSN

  • 免疫原

    Recombinant Protein

  • 细胞定位

    Cytoplasm, Cytoskeleton, Secreted

  • Accession

    P06396

  • 抗体类型

    Polyclonal antibody

  • 抗体同种型

    IgG

  • 反应种属 ?

    Hu, Ms, Mk

  • 阳性样本

    HeLa, A204, PANC-1, C2C12, COS-7

  • 纯化方式

    Immunogen Affinity

  • 浓度

    0.5 mg/ml

  • 标记

    Unconjugated

  • 性状

    Liquid

  • 缓冲体系

    PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300

  • 储存条件

    12 months from date of receipt / reconstitution, -20 °C as supplied

  • 应用

    WB

  • 稀释度

    应用 稀释度 推荐种属
    WB 1:1000-1:2000 Hu, Ms, Mk
背景介绍

  • Gelsolin is a highly conserved, multifunctional actin-binding protein that severs, caps and nucleates actin filaments in response to Ca²⁺ and phosphoinositide signals, thereby orchestrating rapid cytoskeletal remodeling essential for cell motility, endocytosis, apoptosis and immune responses; it exists as both an 80–82 kDa cytoplasmic isoform and a slightly larger secreted plasma variant generated by alternative transcription initiation, each contributing to tissue repair and host defense by clearing actin filaments released from damaged cells, and its dysregulation—through mutation, proteolytic cleavage or altered expression—is implicated in cancer metastasis, neurodegeneration, amyloidosis and other human diseases.

  • 免疫印迹

    • WB result of Gelsolin Rabbit pAb
      Primary antibody: Gelsolin Rabbit pAb at 1/1000 dilution
      Lane 1: HeLa whole cell lysate 20 µg
      Lane 2: A204 whole cell lysate 20 µg
      Lane 3: PANC-1 whole cell lysate 20 µg
      Secondary antibody: Goat Anti-rabbit IgG, (H+L), HRP conjugated at 1/10000 dilution
      Predicted MW: 86 kDa
      Observed MW: 90 kDa

    • WB result of Gelsolin Rabbit pAb
      Primary antibody: Gelsolin Rabbit pAb at 1/1000 dilution
      Lane 1: C2C12 whole cell lysate 20 µg
      Secondary antibody: Goat Anti-rabbit IgG, (H+L), HRP conjugated at 1/10000 dilution
      Predicted MW: 86 kDa
      Observed MW: 90 kDa

    • WB result of Gelsolin Rabbit pAb
      Primary antibody: Gelsolin Rabbit pAb at 1/1000 dilution
      Lane 1: COS-7 whole cell lysate 20 µg
      Secondary antibody: Goat Anti-rabbit IgG, (H+L), HRP conjugated at 1/10000 dilution
      Predicted MW: 86 kDa
      Observed MW: 90 kDa

FAQs

斯达特公司的抗体，可以回收利用几次？

我们一般不推荐客户回收利用抗体。 因为抗体使用之后缓冲体系已经发生改变，不同客户在回收抗体的保存条件上也会有差异，所以抗体回收使用效果无法保证。另外，我们对一批抗体回收验证测试，测试结果显示不同抗体可回收次数不同，一般效价越高的抗体，可重复使用的次数越多，客户可根据实验情况来确定

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