热搜词：
注册
登录
CN
  • CN
  • EN

产品中心 抗体 其他一抗

所有图片（1/3）

FGF21 Recombinant Rabbit mAb (S-2567-21)

Fibroblast growth factor 21,FGF-21

价格 ￥600.00 （ 供应商现货 ： 3-5个工作日）
货号 S0B6338
规格
数量
收藏 分享
产品介绍

产品介绍 FAQs 评论(0)

产品规格

  • 宿主来源

    Rabbit

  • 抗原名称

    FGF21

  • 分子别名

    Fibroblast growth factor 21; FGF-21

  • 免疫原

    Synthetic Peptide

  • 细胞定位

    Secreted

  • Accession

    Q9NSA1

  • 克隆号

    S-2567-21

  • 抗体类型

    Recombinant mAb

  • 抗体同种型

    IgG

  • 反应种属 ?

    Hu, Ms, Rt

  • 阳性样本

    293T, PC-3, U-2 OS, K562, HepG2, C2C12, mouse spleen, rat spleen

  • 纯化方式

    Protein A

  • 浓度

    2 mg/ml

  • 标记

    Unconjugated

  • 性状

    Liquid

  • 缓冲体系

    PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300

  • 储存条件

    12 months from date of receipt / reconstitution, -20 °C as supplied

  • 应用

    WB

  • 稀释度

    应用 稀释度 推荐种属
    WB 1:1000-1:2000 Hu, Ms, Rt
背景介绍

  • Fibroblast growth factor 21 (FGF21) is a 181-amino-acid, liver-derived atypical member of the FGF family that functions as a fasting-induced hormone—binding β-Klotho–FGFR1c complexes in adipose tissue and brain—to orchestrate systemic glucose, lipid and energy homeostasis by promoting insulin sensitivity, enhancing white-fat browning and thermogenesis, suppressing hepatic gluconeogenesis and lipogenesis, and centrally modulating appetite and circadian behavior; its circulating levels surge in response to nutrient deprivation, protein restriction, high-sucrose or high-fat diets, cold exposure, mitochondrial stress and alcoholic or non-alcoholic liver injury, while pharmacologic administration of engineered FGF21 analogs has shown potent, dose-dependent reductions in body weight, plasma triglycerides, LDL-cholesterol and fasting glucose in obese, diabetic and NASH patients, making FGF21 a promising therapeutic target for metabolic disease.

  • 免疫印迹

    • WB result of FGF21 Recombinant Rabbit mAb
      Primary antibody: FGF21 Recombinant Rabbit mAb at 1/1000 dilution
      Lane 1: 293T whole cell lysate 20 µg
      Lane 2: PC-3 whole cell lysate 20 µg
      Lane 3: U-2 OS whole cell lysate 20 µg
      Lane 4: K562 whole cell lysate 20 µg
      Lane 5: HepG2 whole cell lysate 20 µg
      Secondary antibody: Goat Anti-rabbit IgG, (H+L), HRP conjugated at 1/10000 dilution
      Predicted MW: 22 kDa
      Observed MW: 22 kDa

    • WB result of FGF21 Recombinant Rabbit mAb
      Primary antibody: FGF21 Recombinant Rabbit mAb at 1/1000 dilution
      Lane 1: C2C12 whole cell lysate 20 µg
      Lane 2: mouse spleen lysate 20 µg
      Secondary antibody: Goat Anti-rabbit IgG, (H+L), HRP conjugated at 1/10000 dilution
      Predicted MW: 22 kDa
      Observed MW: 22 kDa

    • WB result of FGF21 Recombinant Rabbit mAb
      Primary antibody: FGF21 Recombinant Rabbit mAb at 1/1000 dilution
      Lane 1: rat spleen lysate 20 µg
      Secondary antibody: Goat Anti-rabbit IgG, (H+L), HRP conjugated at 1/10000 dilution
      Predicted MW: 22 kDa
      Observed MW: 22 kDa

FAQs

斯达特公司的抗体，可以回收利用几次？

我们一般不推荐客户回收利用抗体。 因为抗体使用之后缓冲体系已经发生改变，不同客户在回收抗体的保存条件上也会有差异，所以抗体回收使用效果无法保证。另外，我们对一批抗体回收验证测试，测试结果显示不同抗体可回收次数不同，一般效价越高的抗体，可重复使用的次数越多，客户可根据实验情况来确定

评论(0)