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CTGF Recombinant Rabbit mAb (S-3356)

CCN family member 2,Cellular communication network factor 2Imported,Connective tissue growth factor,Hypertrophic chondrocyte-specific protein 24,Insulin-like growth factor-binding protein 8 (IBP-8,IGF-binding protein 8,IGFBP-8),HCS24,IGFBP8,CCN2

Datasheet COA

价格￥600.00 （供应商现货： 3-5个工作日）

货号 S0B6253

规格

25μl100μl1ml

数量

产品介绍

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产品规格

宿主来源

Rabbit
抗原名称

CTGF
分子别名

CCN family member 2; Cellular communication network factor 2Imported; Connective tissue growth factor; Hypertrophic chondrocyte-specific protein 24; Insulin-like growth factor-binding protein 8 (IBP-8; IGF-binding protein 8; IGFBP-8); HCS24; IGFBP8; CCN2
细胞定位

Secreted
Accession

P29279
克隆号

S-3356
抗体类型

Recombinant mAb
抗体同种型

IgG
反应种属 ?

Hu
阳性样本

HT-1080, HepG2, PANC-1
纯化方式

Protein A
浓度

0.5 mg/ml
标记

Unconjugated
性状

Liquid
缓冲体系

PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300
储存条件

12 months from date of receipt / reconstitution, -20 °C as supplied
应用

WB
稀释度

应用稀释度推荐种属

WB 1:1000-1:5000 Hu

应用	稀释度	推荐种属
WB	1:1000-1:5000	Hu

背景介绍

Connective tissue growth factor (CTGF, also termed CCN2) is a 38 kDa, cysteine-rich, secreted matricellular protein of the CCN family that orchestrates cell adhesion, migration, proliferation, differentiation, angiogenesis, and extracellular matrix (ECM) remodeling by binding integrins, heparan sulfate proteoglycans, and growth factors such as TGF-β and VEGF through its four conserved domains (IGFBP, VWC, TSP-1, and cysteine-knot CT); physiologically it is indispensable for embryonic skeletal, pancreatic, ovarian, and vascular development, whereas dysregulated CTGF drives fibrosis, diabetic retinopathy, atherosclerosis, and tumorigenesis, making it a prominent therapeutic target now being pursued with monoclonal antibodies in pre-clinical and clinical trials.

免疫印迹
- WB result of CTGF Recombinant Rabbit mAb
  Primary antibody: CTGF Recombinant Rabbit mAb at 1/1000 dilution
  Lane 1: MCF7 whole cell lysate 20 µg
  Lane 2: HT-1080 whole cell lysate 20 µg
  Lane 3: HepG2 whole cell lysate 20 µg
  Lane 4: PANC-1 whole cell lysate 20 µg
  Negative control: MCF7 whole cell lysate
  Secondary antibody: Goat Anti-rabbit IgG, (H+L), HRP conjugated at 1/10000 dilution
  Predicted MW: 36 kDa
  Observed MW: 36 kDa