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Dopamine D (2) Receptor/D2R Recombinant Rabbit mAb (S-2127-37)

D (2) dopamine receptor,Dopamine D2 receptor,DRD2

价格 ￥600.00 （ 供应商现货 ： 3-5个工作日）
货号 S0B6050
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产品介绍

产品介绍 FAQs 评论(0)

产品规格

  • 宿主来源

    Rabbit

  • 抗原名称

    Dopamine D (2) Receptor/D2R

  • 分子别名

    D (2) dopamine receptor; Dopamine D2 receptor; DRD2

  • 免疫原

    Synthetic Peptide

  • 细胞定位

    Cell membrane

  • Accession

    P14416

  • 克隆号

    S-2127-37

  • 抗体类型

    Recombinant mAb

  • 抗体同种型

    IgG

  • 反应种属 ?

    Hu, Ms, Rt

  • 阳性样本

    Caco-2, SH-SY5Y, PANC-1, mouse brain, rat brain

  • 纯化方式

    Protein A

  • 浓度

    0.5 mg/ml

  • 标记

    Unconjugated

  • 性状

    Liquid

  • 缓冲体系

    PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300

  • 储存条件

    12 months from date of receipt / reconstitution, -20 °C as supplied

  • 应用

    WB

  • 稀释度

    应用 稀释度 推荐种属
    WB 1:1000 Hu, Ms, Rt
背景介绍

  • The dopamine D2 receptor (D2R) is a G protein-coupled receptor encoded by the DRD2 gene, playing a crucial role in the central nervous system. It is the main target for most antipsychotic drugs and is involved in regulating various functions such as motor control, reward, and memory. D2R is coupled to the Gi subtype of G protein, inhibiting adenylyl cyclase activity. In addition to its canonical G protein signaling, D2R also signals through β-arrestin pathways, which can be selectively targeted to potentially improve therapeutic outcomes. Research has shown that D2R is involved in synaptic plasticity and memory formation in mice, and it may protect dopamine neurons from cell death in conditions mimicking Parkinson's disease.

  • 免疫印迹

    • WB result of Dopamine D(2) Receptor/D2R Recombinant Rabbit mAb
      Primary antibody: Dopamine D(2) Receptor/D2R Recombinant Rabbit mAb at 1/1000 dilution
      Lane 1: Caco-2 whole cell lysate 20 µg
      Lane 2: SH-SY5Y whole cell lysate 20 µg
      Lane 3: PANC-1 whole cell lysate 20 µg
      Secondary antibody: Goat Anti-rabbit IgG, (H+L), HRP conjugated at 1/10000 dilution
      Predicted MW: 50 kDa
      Observed MW: 50 kDa

    • WB result of Dopamine D(2) Receptor/D2R Recombinant Rabbit mAb
      Primary antibody: Dopamine D(2) Receptor/D2R Recombinant Rabbit mAb at 1/1000 dilution
      Lane 1: mouse brain lysate 20 µg
      Secondary antibody: Goat Anti-rabbit IgG, (H+L), HRP conjugated at 1/10000 dilution
      Predicted MW: 50 kDa
      Observed MW: 50 kDa

    • WB result of Dopamine D(2) Receptor/D2R Recombinant Rabbit mAb
      Primary antibody: Dopamine D(2) Receptor/D2R Recombinant Rabbit mAb at 1/1000 dilution
      Lane 1: rat brain lysate 20 µg
      Secondary antibody: Goat Anti-rabbit IgG, (H+L), HRP conjugated at 1/10000 dilution
      Predicted MW: 50 kDa
      Observed MW: 50 kDa

FAQs

斯达特公司的抗体，可以回收利用几次？

我们一般不推荐客户回收利用抗体。 因为抗体使用之后缓冲体系已经发生改变，不同客户在回收抗体的保存条件上也会有差异，所以抗体回收使用效果无法保证。另外，我们对一批抗体回收验证测试，测试结果显示不同抗体可回收次数不同，一般效价越高的抗体，可重复使用的次数越多，客户可根据实验情况来确定

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