SMAD7 Mouse mAb
SMAD family member 7,SMAD 7 Curated,hSMAD7,Mothers against decapentaplegic homolog 7 (MAD homolog 7,Mothers against DPP homolog 7),Mothers against decapentaplegic homolog 8 (MAD homolog 8,Mothers against DPP homolog 8),MADH7,MADH8,SMAD7
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宿主来源
Mouse抗原名称
SMAD7分子别名
SMAD family member 7; SMAD 7 Curated; hSMAD7; Mothers against decapentaplegic homolog 7 (MAD homolog 7; Mothers against DPP homolog 7); Mothers against decapentaplegic homolog 8 (MAD homolog 8; Mothers against DPP homolog 8); MADH7; MADH8; SMAD7细胞定位
Cytoplasm, NucleusAccession
O15105抗体类型
Mouse mAb抗体同种型
IgG2a反应种属 ?
Ms, Rt阳性样本
mouse kidney, rat kidney纯化方式
Protein A浓度
1 mg/ml标记
Unconjugated性状
Liquid缓冲体系
PBS, 40% Glycerol, 0.05% BSA, 0.02% sodium azide
储存条件
12 months from date of receipt / reconstitution, -20 °C as supplied
应用
WB
稀释度
应用 稀释度 推荐种属 WB 1:5000 Ms, Rt
SMAD7 is a crucial inhibitory protein that acts as a negative regulator of the TGF-β signaling pathway. It maintains cellular homeostasis by binding to activated TGF-β receptors and preventing the phosphorylation of downstream SMAD proteins. Clinically, dysregulation of SMAD7 is closely associated with various pathologies, including colorectal cancer, fibrosis, and inflammatory bowel disease, making it a potential therapeutic target.
免疫印迹
WB result of SMAD7 Mouse mAb
Primary antibody: SMAD7 Mouse mAb at 1/5000 dilution
Lane 1: mouse kidney lysate 20 µg
Secondary antibody: Goat Anti-mouse IgG, (H+L), HRP conjugated at 1/10000 dilution
Predicted MW: 46 kDa
Observed MW: 52 kDa
This blot was developed with high sensitivity substrateWB result of SMAD7 Mouse mAb
Primary antibody: SMAD7 Mouse mAb at 1/5000 dilution
Lane 1: rat kidney lysate 20 µg
Secondary antibody: Goat Anti-mouse IgG, (H+L), HRP conjugated at 1/10000 dilution
Predicted MW: 46 kDa
Observed MW: 52 kDa
This blot was developed with high sensitivity substrate
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