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IGSF8 Recombinant Rabbit mAb (S-2101-8)

Immunoglobulin superfamily member 8,CD81 partner 3,Glu-Trp-Ile EWI motif-containing protein 2 (EWI-2),Keratinocytes-associated transmembrane protein 4 (KCT-4),LIR-D1,Prostaglandin regulatory-like protein (PGRL),CD316,CD81P3,EWI2,KCT4

Datasheet COA

价格￥600.00 （供应商现货： 3-5个工作日）

货号 S0B6015

规格

25μl100μl1ml

数量

产品介绍

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产品规格

宿主来源

Rabbit
抗原名称

IGSF8
分子别名

Immunoglobulin superfamily member 8; CD81 partner 3; Glu-Trp-Ile EWI motif-containing protein 2 (EWI-2); Keratinocytes-associated transmembrane protein 4 (KCT-4); LIR-D1; Prostaglandin regulatory-like protein (PGRL); CD316; CD81P3; EWI2; KCT4
免疫原

Recombinant Protein
细胞定位

Cell membrane
Accession

Q969P0
克隆号

S-2101-8
抗体类型

Recombinant mAb
抗体同种型

IgG
反应种属 ?

Hu, Ms, Rt
阳性样本

HepG2, Jurkat, NIH/3T3, C6
纯化方式

Protein A
浓度

0.5 mg/ml
标记

Unconjugated
性状

Liquid
缓冲体系

PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300
储存条件

12 months from date of receipt / reconstitution, -20 °C as supplied
应用

WB
稀释度

应用稀释度推荐种属

WB 1:1000 Hu, Ms, Rt

应用	稀释度	推荐种属
WB	1:1000	Hu, Ms, Rt

背景介绍

Immunoglobulin superfamily member 8 (IGSF8), also known as CD316, is a protein encoded by the IGSF8 gene in humans. It is an innate immune checkpoint that inhibits the cytotoxic activity of natural killer (NK) cells by binding to the Killer Ig-like Receptor KIR3DL2. IGSF8 is a member of the EWI subfamily of the immunoglobulin protein superfamily, containing a single transmembrane domain, an EWI motif, and a variable number of immunoglobulin domains. It interacts with tetraspanins CD81 and CD9, regulating their roles in various cellular functions, including cell migration and viral infection. IGSF8 may also function as a tumor suppressor by inhibiting the proliferation of certain cancers.

免疫印迹
- WB result of IGSF8 Recombinant Rabbit mAb
  Primary antibody: IGSF8 Recombinant Rabbit mAb at 1/1000 dilution
  Lane 1: HepG2 whole cell lysate 20 µg
  Lane 2: Jurkat whole cell lysate 20 µg
  Secondary antibody: Goat Anti-rabbit IgG, (H+L), HRP conjugated at 1/10000 dilution
  Predicted MW: 65 kDa
  Observed MW: 72 kDa
  This blot was developed with high sensitivity substrate
- WB result of IGSF8 Recombinant Rabbit mAb
  Primary antibody: IGSF8 Recombinant Rabbit mAb at 1/1000 dilution
  Lane 1: NIH/3T3 whole cell lysate 20 µg
  Secondary antibody: Goat Anti-rabbit IgG, (H+L), HRP conjugated at 1/10000 dilution
  Predicted MW: 65 kDa
  Observed MW: 80 kDa
  This blot was developed with high sensitivity substrate
- WB result of IGSF8 Recombinant Rabbit mAb
  Primary antibody: IGSF8 Recombinant Rabbit mAb at 1/1000 dilution
  Lane 1: C6 whole cell lysate 20 µg
  Secondary antibody: Goat Anti-rabbit IgG, (H+L), HRP conjugated at 1/10000 dilution
  Predicted MW: 65 kDa
  Observed MW: 80 kDa
  This blot was developed with high sensitivity substrate